Effects of a Peripherally Restricted Hybrid Inhibitor of CB1 Receptors and iNOS on Alcohol Drinking Behavior and Alcohol-Induced Endotoxemia

Effects of a Peripherally Restricted Hybrid Inhibitor of CB1 Receptors and iNOS on Alcohol Drinking Behavior and Alcohol-Induced Endotoxemia

Alcohol consumption is associated with gut dysbiosis, increased intestinal permeability, endotoxemia, and a cascade that leads to persistent systemic inflammation, alcoholic liver disease, and other ailments. Craving for alcohol and its consequences depends, among other things, on the endocannabinoi...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Luis Santos-Molina, Alexa Herrerias, Charles N. Zawatsky, Ozge Gunduz-Cinar, Resat Cinar, Malliga R. Iyer, Casey M. Wood, Yuhong Lin, Bin Gao, George Kunos, Grzegorz Godlewski
Format: Artykuł
Język:English
Wydane: MDPI AG 2021-08-01
Seria:Molecules
Hasła przedmiotowe:
cannabinoid
MRI-1867
hybrid ligand
CB1 receptor antagonist
iNOS inhibitor
rimonabant
Dostęp online:https://www.mdpi.com/1420-3049/26/16/5089

Internet

https://www.mdpi.com/1420-3049/26/16/5089

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