A human multi-lineage hepatic organoid model for liver fibrosis
Autosomal recessive polycystic kidney disease (ARPKD) is a genetic disorder which is associated with kidney and liver pathology, including liver fibrosis. Here the authors develop and characterize human liver organoids with a ARPKD mutation, and find that they show aspects of the pathology, includin...
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Bibliographic Details
| Main Authors: |
Yuan Guan,
Annika Enejder,
Meiyue Wang,
Zhuoqing Fang,
Lu Cui,
Shih-Yu Chen,
Jingxiao Wang,
Yalun Tan,
Manhong Wu,
Xinyu Chen,
Patrik K. Johansson,
Issra Osman,
Koshi Kunimoto,
Pierre Russo,
Sarah C. Heilshorn,
Gary Peltz |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2021-10-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-021-26410-9
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