3,3′-Diindolylmethane Suppresses the Growth of Hepatocellular Carcinoma by Regulating Its Invasion, Migration, and ER Stress-Mediated Mitochondrial Apoptosis

3,3′-Diindolylmethane Suppresses the Growth of Hepatocellular Carcinoma by Regulating Its Invasion, Migration, and ER Stress-Mediated Mitochondrial Apoptosis

Hepatocellular carcinoma (HCC) is the leading cause of cancer-related death worldwide with limited treatment options. Biomarker-based active phenolic flavonoids isolated from medicinal plants might shed some light on potential therapeutics for treating HCC. 3,3′-diindolylmethane (DIM) is a unique bi...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Suvesh Munakarmi, Juna Shrestha, Hyun-Beak Shin, Geum-Hwa Lee, Yeon-Jun Jeong
Format: Artikel
Sprache:English
Veröffentlicht: MDPI AG 2021-05-01
Schriftenreihe:Cells
Schlagworte:
ER stress
unfolded protein response
hepatocellular carcinoma
apoptosis
EMT
DIM
Online Zugang:https://www.mdpi.com/2073-4409/10/5/1178

Online

https://www.mdpi.com/2073-4409/10/5/1178

Ähnliche Einträge