Malignant Melanoma Arising in an Ovarian Mature Cystic Teratoma - A Rare Entity

Mature cystic teratomas, also known as dermoid cysts, are composed of a mixture of tissues derived from all three germ layers and constitute about 20% of all ovarian neoplasms. However, malignant transformation in a mature cystic teratoma is an uncommon event occurring only in about 1.8% cases. A...

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Main Authors: RANJINI KUDVA, GAURI SALGAONKAR AYACHIT, ANURAG AYACHIT
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2015-04-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/5817/12457_CE[Ra_Ash]_F(P)_PF1(NJAK)_PFA(AK)_PF2(PAG).pdf
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author RANJINI KUDVA
GAURI SALGAONKAR AYACHIT
ANURAG AYACHIT
author_facet RANJINI KUDVA
GAURI SALGAONKAR AYACHIT
ANURAG AYACHIT
author_sort RANJINI KUDVA
collection DOAJ
description Mature cystic teratomas, also known as dermoid cysts, are composed of a mixture of tissues derived from all three germ layers and constitute about 20% of all ovarian neoplasms. However, malignant transformation in a mature cystic teratoma is an uncommon event occurring only in about 1.8% cases. A variety of tumours can arise within a mature cystic teratoma (most common being squamous cell carcinoma), with malignant melanoma being extremely rare among such tumors. While most authors believe that primary ovarian melanoma almost always arises within a mature cystic teratoma, the primary nature of an ovarian malignant melanoma can be ascertained only once metastasis from a cutaneous melanoma is ruled out. The first case of malignant melanoma arising in an ovarian mature cystic teratoma was reported in 1901 and only about 45 additional cases have been reported till date. We present another case of a primary malignant melanoma arising within a mature cystic teratoma.
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spelling doaj.art-a0ac26e4893642b387296c20896f6d812022-12-21T18:58:35ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2015-04-0194ED14ED1610.7860/JCDR/2015/12457.5817Malignant Melanoma Arising in an Ovarian Mature Cystic Teratoma - A Rare EntityRANJINI KUDVA0GAURI SALGAONKAR AYACHIT1ANURAG AYACHIT2Professor, Department of Pathology, Kasturba Medical College, Manipal, Karnataka, India.Assistant Professor, Department of Pathology, Kasturba Medical College, Manipal, Karnataka, India.Associate Professor, Department of Radiodiagnosis & Imaging, Kasturba Medical College, Manipal, Karnataka, India.Mature cystic teratomas, also known as dermoid cysts, are composed of a mixture of tissues derived from all three germ layers and constitute about 20% of all ovarian neoplasms. However, malignant transformation in a mature cystic teratoma is an uncommon event occurring only in about 1.8% cases. A variety of tumours can arise within a mature cystic teratoma (most common being squamous cell carcinoma), with malignant melanoma being extremely rare among such tumors. While most authors believe that primary ovarian melanoma almost always arises within a mature cystic teratoma, the primary nature of an ovarian malignant melanoma can be ascertained only once metastasis from a cutaneous melanoma is ruled out. The first case of malignant melanoma arising in an ovarian mature cystic teratoma was reported in 1901 and only about 45 additional cases have been reported till date. We present another case of a primary malignant melanoma arising within a mature cystic teratoma.https://jcdr.net/articles/PDF/5817/12457_CE[Ra_Ash]_F(P)_PF1(NJAK)_PFA(AK)_PF2(PAG).pdfca19.9ca125ceahmb-45ovarian dermoid cystovarian malignant melanoma
spellingShingle RANJINI KUDVA
GAURI SALGAONKAR AYACHIT
ANURAG AYACHIT
Malignant Melanoma Arising in an Ovarian Mature Cystic Teratoma - A Rare Entity
Journal of Clinical and Diagnostic Research
ca19.9
ca125
cea
hmb-45
ovarian dermoid cyst
ovarian malignant melanoma
title Malignant Melanoma Arising in an Ovarian Mature Cystic Teratoma - A Rare Entity
title_full Malignant Melanoma Arising in an Ovarian Mature Cystic Teratoma - A Rare Entity
title_fullStr Malignant Melanoma Arising in an Ovarian Mature Cystic Teratoma - A Rare Entity
title_full_unstemmed Malignant Melanoma Arising in an Ovarian Mature Cystic Teratoma - A Rare Entity
title_short Malignant Melanoma Arising in an Ovarian Mature Cystic Teratoma - A Rare Entity
title_sort malignant melanoma arising in an ovarian mature cystic teratoma a rare entity
topic ca19.9
ca125
cea
hmb-45
ovarian dermoid cyst
ovarian malignant melanoma
url https://jcdr.net/articles/PDF/5817/12457_CE[Ra_Ash]_F(P)_PF1(NJAK)_PFA(AK)_PF2(PAG).pdf
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AT anuragayachit malignantmelanomaarisinginanovarianmaturecysticteratomaarareentity