Lipid Flippase Subunit Cdc50 Mediates Drug Resistance and Virulence in <named-content content-type="genus-species">Cryptococcus neoformans</named-content>

Lipid Flippase Subunit Cdc50 Mediates Drug Resistance and Virulence in <named-content content-type="genus-species">Cryptococcus neoformans</named-content>

ABSTRACT Cryptococcus neoformans is a human fungal pathogen and a major cause of fungal meningitis in immunocompromised individuals. Treatment options for cryptococcosis are limited. Of the two major antifungal drug classes, azoles are active against C. neoformans but exert a fungistatic effect, nec...

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Bibliographic Details
Main Authors: Wei Huang, Guojian Liao, Gregory M. Baker, Yina Wang, Richard Lau, Padmaja Paderu, David S. Perlin, Chaoyang Xue
Format: Article
Language:English
Published: American Society for Microbiology 2016-07-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00478-16

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