Effect of Distance from Catalytic Synergy Group to Iron Porphyrin Center on Activity of G-Quadruplex/Hemin DNAzyme

Effect of Distance from Catalytic Synergy Group to Iron Porphyrin Center on Activity of G-Quadruplex/Hemin DNAzyme

G-quadruplex/Hemin (G4/Hemin) complex has been widely used in biocatalysis and analytical applications. Meanwhile, compared with natural proteinous enzyme, its low catalytic activity is still limiting its applications. Even though several methods have been developed to enhance the peroxidation effic...

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Bibliographic Details
Main Authors: Dehui Qiu, Jingang Mo, Yuan Liu, Jiangyan Zhang, Yongqiang Cheng, Xiaobo Zhang
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Molecules
Subjects:
G-quadruplex/Hemin
DNAzyme
catalytic activity
catalytic mechanism
second-cytosine
distance regulation
Online Access:https://www.mdpi.com/1420-3049/25/15/3425

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