Primary aldosteronism and lower-extremity arterial disease: a two-sample Mendelian randomization study

Primary aldosteronism and lower-extremity arterial disease: a two-sample Mendelian randomization study

Abstract Background and Aims Primary aldosteronism (PA) is an adrenal disorder of autonomous aldosterone secretion which promotes arterial injury. We aimed to explore whether PA is causally associated with lower-extremity arterial disease (LEAD). Methods We included 39,713 patients with diabetes and...

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Bibliographic Details
Main Authors: Jinbo Hu, Qinglian Zeng, Xiangjun Chen, Wenjin Luo, Ziwei Tang, Mei Mei, Wenrui Zhao, Zhipeng Du, Zhiping Liu, Qifu Li, Qingfeng Cheng, Shumin Yang
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Cardiovascular Diabetology
Subjects:
Primary aldosteronism
Lower-extremity arterial disease
Diabetes
Mendelian randomization
Causal relationship
Online Access:https://doi.org/10.1186/s12933-023-02086-x

Internet

https://doi.org/10.1186/s12933-023-02086-x

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