Targeting DNA Repair Pathways in Hematological Malignancies

Targeting DNA Repair Pathways in Hematological Malignancies

DNA repair plays an essential role in protecting cells that are repeatedly exposed to endogenous or exogenous insults that can induce varying degrees of DNA damage. Any defect in DNA repair mechanisms results in multiple genomic changes that ultimately may result in mutation, tumor growth, and/or ce...

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Bibliographic Details
Main Authors: Jehad F. Alhmoud, Ayman G. Mustafa, Mohammed Imad Malki
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
DNA repair
DNA damage
hematological malignancies
apoptosis
mutation
Online Access:https://www.mdpi.com/1422-0067/21/19/7365

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