CNApp, a tool for the quantification of copy number alterations and integrative analysis revealing clinical implications

CNApp, a tool for the quantification of copy number alterations and integrative analysis revealing clinical implications

Somatic copy number alterations (CNAs) are a hallmark of cancer, but their role in tumorigenesis and clinical relevance remain largely unclear. Here, we developed CNApp, a web-based tool that allows a comprehensive exploration of CNAs by using purity-corrected segmented data from multiple genomic pl...

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Bibliographic Details
Main Authors: Sebastià Franch-Expósito, Laia Bassaganyas, Maria Vila-Casadesús, Eva Hernández-Illán, Roger Esteban-Fabró, Marcos Díaz-Gay, Juan José Lozano, Antoni Castells, Josep Maria Llovet, Sergi Castellví-Bel, Jordi Camps
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-01-01
Series:eLife
Subjects:
copy number alterations
cancer genomics
CNA scores
pan-cancer
colorectal cancer
hepatocellular carcinoma
Online Access:https://elifesciences.org/articles/50267

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