Comparative proteomics analysis suggests that placental mitochondria are involved in the development of pre-eclampsia.

INTRODUCTION: Pre-eclampsia (PE), a severe pregnancy-specific disease characterized by the new onset of hypertension, proteinuria, edema, and a series of other systematic disorders, is a state of widespread mitochondrial dysfunction of the placenta. METHODS: We compared the morphology of mitochondri...

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Bibliographic Details
Main Authors: Zhonghua Shi, Wei Long, Chun Zhao, Xirong Guo, Rong Shen, Hongjuan Ding
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3650054?pdf=render