Aqueous amine enables sustainable monosaccharide, monophenol, and pyridine base coproduction in lignocellulosic biorefineries
Abstract Thought-out utilization of entire lignocellulose is of great importance to achieving sustainable and cost-effective biorefineries. However, there is a trade-off between efficient carbohydrate utilization and lignin-to-chemical conversion yield. Here, we fractionate corn stover into a carboh...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2024-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-45073-w |
| _version_ | 1797276418772566016 |
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| author | Li Xu Meifang Cao Jiefeng Zhou Yuxia Pang Zhixian Li Dongjie Yang Shao-Yuan Leu Hongming Lou Xuejun Pan Xueqing Qiu |
| author_facet | Li Xu Meifang Cao Jiefeng Zhou Yuxia Pang Zhixian Li Dongjie Yang Shao-Yuan Leu Hongming Lou Xuejun Pan Xueqing Qiu |
| author_sort | Li Xu |
| collection | DOAJ |
| description | Abstract Thought-out utilization of entire lignocellulose is of great importance to achieving sustainable and cost-effective biorefineries. However, there is a trade-off between efficient carbohydrate utilization and lignin-to-chemical conversion yield. Here, we fractionate corn stover into a carbohydrate fraction with high enzymatic digestibility and reactive lignin with satisfactory catalytic depolymerization activity using a mild high-solid process with aqueous diethylamine (DEA). During the fractionation, in situ amination of lignin achieves extensive delignification, effective lignin stabilization, and dramatically reduced nonproductive adsorption of cellulase on the substrate. Furthermore, by designing a tandem fractionation-hydrogenolysis strategy, the dissolved lignin is depolymerized and aminated simultaneously to co-produce monophenolics and pyridine bases. The process represents the viable scheme of transforming real lignin into pyridine bases in high yield, resulting from the reactions between cleaved lignin side chains and amines. This work opens a promising approach to the efficient valorization of lignocellulose. |
| first_indexed | 2024-03-07T15:27:59Z |
| format | Article |
| id | doaj.art-a0b4e8428d424695ba59aef869aa06c2 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-03-07T15:27:59Z |
| publishDate | 2024-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-a0b4e8428d424695ba59aef869aa06c22024-03-05T16:35:57ZengNature PortfolioNature Communications2041-17232024-01-0115111210.1038/s41467-024-45073-wAqueous amine enables sustainable monosaccharide, monophenol, and pyridine base coproduction in lignocellulosic biorefineriesLi Xu0Meifang Cao1Jiefeng Zhou2Yuxia Pang3Zhixian Li4Dongjie Yang5Shao-Yuan Leu6Hongming Lou7Xuejun Pan8Xueqing Qiu9Guangdong Provincial Key Lab of Green Chemical Product Technology, State Key Laboratory of Pulp and Paper Engineering, School of Chemistry and Chemical Engineering, South China University of TechnologyGuangdong Provincial Key Lab of Green Chemical Product Technology, State Key Laboratory of Pulp and Paper Engineering, School of Chemistry and Chemical Engineering, South China University of TechnologyGuangdong Provincial Key Lab of Green Chemical Product Technology, State Key Laboratory of Pulp and Paper Engineering, School of Chemistry and Chemical Engineering, South China University of TechnologyGuangdong Provincial Key Lab of Green Chemical Product Technology, State Key Laboratory of Pulp and Paper Engineering, School of Chemistry and Chemical Engineering, South China University of TechnologyGuangdong Provincial Key Lab of Green Chemical Product Technology, State Key Laboratory of Pulp and Paper Engineering, School of Chemistry and Chemical Engineering, South China University of TechnologyGuangdong Provincial Key Lab of Green Chemical Product Technology, State Key Laboratory of Pulp and Paper Engineering, School of Chemistry and Chemical Engineering, South China University of TechnologyDepartment of Civil and Environmental Engineering, The Hong Kong Polytechnic UniversityGuangdong Provincial Key Lab of Green Chemical Product Technology, State Key Laboratory of Pulp and Paper Engineering, School of Chemistry and Chemical Engineering, South China University of TechnologyDepartment of Biological Systems Engineering, University of Wisconsin-MadisonSchool of Chemical Engineering and Light Industry, Guangdong University of TechnologyAbstract Thought-out utilization of entire lignocellulose is of great importance to achieving sustainable and cost-effective biorefineries. However, there is a trade-off between efficient carbohydrate utilization and lignin-to-chemical conversion yield. Here, we fractionate corn stover into a carbohydrate fraction with high enzymatic digestibility and reactive lignin with satisfactory catalytic depolymerization activity using a mild high-solid process with aqueous diethylamine (DEA). During the fractionation, in situ amination of lignin achieves extensive delignification, effective lignin stabilization, and dramatically reduced nonproductive adsorption of cellulase on the substrate. Furthermore, by designing a tandem fractionation-hydrogenolysis strategy, the dissolved lignin is depolymerized and aminated simultaneously to co-produce monophenolics and pyridine bases. The process represents the viable scheme of transforming real lignin into pyridine bases in high yield, resulting from the reactions between cleaved lignin side chains and amines. This work opens a promising approach to the efficient valorization of lignocellulose.https://doi.org/10.1038/s41467-024-45073-w |
| spellingShingle | Li Xu Meifang Cao Jiefeng Zhou Yuxia Pang Zhixian Li Dongjie Yang Shao-Yuan Leu Hongming Lou Xuejun Pan Xueqing Qiu Aqueous amine enables sustainable monosaccharide, monophenol, and pyridine base coproduction in lignocellulosic biorefineries Nature Communications |
| title | Aqueous amine enables sustainable monosaccharide, monophenol, and pyridine base coproduction in lignocellulosic biorefineries |
| title_full | Aqueous amine enables sustainable monosaccharide, monophenol, and pyridine base coproduction in lignocellulosic biorefineries |
| title_fullStr | Aqueous amine enables sustainable monosaccharide, monophenol, and pyridine base coproduction in lignocellulosic biorefineries |
| title_full_unstemmed | Aqueous amine enables sustainable monosaccharide, monophenol, and pyridine base coproduction in lignocellulosic biorefineries |
| title_short | Aqueous amine enables sustainable monosaccharide, monophenol, and pyridine base coproduction in lignocellulosic biorefineries |
| title_sort | aqueous amine enables sustainable monosaccharide monophenol and pyridine base coproduction in lignocellulosic biorefineries |
| url | https://doi.org/10.1038/s41467-024-45073-w |
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