Defining the Role of Metastasis-Initiating Cells in Promoting Carcinogenesis in Ovarian Cancer

Defining the Role of Metastasis-Initiating Cells in Promoting Carcinogenesis in Ovarian Cancer

Ovarian cancer is the deadliest gynecological malignancy with a high prevalence of transcoelomic metastasis. Metastasis is a multi-step process and only a small percentage of cancer cells, metastasis-initiating cells (MICs), have the capacity to finally establish metastatic lesions. These MICs maint...

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Bibliographic Details
Main Authors: Ji Wang, James C. Ford, Anirban K. Mitra
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Biology
Subjects:
ovarian cancer
metastasis
metastasis-initiating cells
microenvironment
Online Access:https://www.mdpi.com/2079-7737/12/12/1492

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