Optimization of Oleuropein and Luteolin-7-O-Glucoside Extraction from Olive Leaves by Ultrasound-Assisted Technology
The olive orchard cultivation in Mediterranean countries results in huge amounts of lignocellulosic biomass residues. One of the main residues are olive leaves. Olive leaves contain high concentrations of bioactive antioxidant compounds like oleuropein and luteolin-7-glucoside. The production of bia...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-06-01
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| Series: | Energies |
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| Online Access: | https://www.mdpi.com/1996-1073/12/13/2486 |
| _version_ | 1811301266835374080 |
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| author | Antonio Lama-Muñoz María del Mar Contreras Francisco Espínola Manuel Moya Inmaculada Romero Eulogio Castro |
| author_facet | Antonio Lama-Muñoz María del Mar Contreras Francisco Espínola Manuel Moya Inmaculada Romero Eulogio Castro |
| author_sort | Antonio Lama-Muñoz |
| collection | DOAJ |
| description | The olive orchard cultivation in Mediterranean countries results in huge amounts of lignocellulosic biomass residues. One of the main residues are olive leaves. Olive leaves contain high concentrations of bioactive antioxidant compounds like oleuropein and luteolin-7-glucoside. The production of biactive compounds from olive leaves requires treatments capable of breaking the lignocellulosic structure. Current research focuses on use of inexpensive, quick, and not harmful to the environment treatments, searching a more simplified large-scale operation approach. Recently, advances in applied chemistry have led to possible new emerging industrial techniques like ultrasound-assisted extraction (UAE). This technology is a promising candidate as a green treatment solution for olive leaves utilization in a biorefinery. However, this application goes through prior optimization of technique and operating conditions. The goal of this study was to optimize the extraction of oleuropein and luteolin-7-glucoside from olive leaves through an investigation of the influence of key factors of ultrasound-assisted extraction using an experimental central composite design, in comparison with conventional Soxhlet extraction. The highest extraction efficiency and antioxidant capacity were obtained under optimal increment of temperature and amplitude conditions (40 °C and 30%, respectively). Values for oleuropein, luteolin-7-glucoside were 69.91 g/kg and 1.82 g/kg, respectively. |
| first_indexed | 2024-04-13T07:06:59Z |
| format | Article |
| id | doaj.art-a0ba2b524986414f8134e32d268fe575 |
| institution | Directory Open Access Journal |
| issn | 1996-1073 |
| language | English |
| last_indexed | 2024-04-13T07:06:59Z |
| publishDate | 2019-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Energies |
| spelling | doaj.art-a0ba2b524986414f8134e32d268fe5752022-12-22T02:56:59ZengMDPI AGEnergies1996-10732019-06-011213248610.3390/en12132486en12132486Optimization of Oleuropein and Luteolin-7-O-Glucoside Extraction from Olive Leaves by Ultrasound-Assisted TechnologyAntonio Lama-Muñoz0María del Mar Contreras1Francisco Espínola2Manuel Moya3Inmaculada Romero4Eulogio Castro5Department of Chemical, Environmental and Materials Engineering, University of Jaén, Campus Las Lagunillas, s/n, Building B3, 23071 Jaén, SpainDepartment of Chemical, Environmental and Materials Engineering, University of Jaén, Campus Las Lagunillas, s/n, Building B3, 23071 Jaén, SpainDepartment of Chemical, Environmental and Materials Engineering, University of Jaén, Campus Las Lagunillas, s/n, Building B3, 23071 Jaén, SpainDepartment of Chemical, Environmental and Materials Engineering, University of Jaén, Campus Las Lagunillas, s/n, Building B3, 23071 Jaén, SpainDepartment of Chemical, Environmental and Materials Engineering, University of Jaén, Campus Las Lagunillas, s/n, Building B3, 23071 Jaén, SpainDepartment of Chemical, Environmental and Materials Engineering, University of Jaén, Campus Las Lagunillas, s/n, Building B3, 23071 Jaén, SpainThe olive orchard cultivation in Mediterranean countries results in huge amounts of lignocellulosic biomass residues. One of the main residues are olive leaves. Olive leaves contain high concentrations of bioactive antioxidant compounds like oleuropein and luteolin-7-glucoside. The production of biactive compounds from olive leaves requires treatments capable of breaking the lignocellulosic structure. Current research focuses on use of inexpensive, quick, and not harmful to the environment treatments, searching a more simplified large-scale operation approach. Recently, advances in applied chemistry have led to possible new emerging industrial techniques like ultrasound-assisted extraction (UAE). This technology is a promising candidate as a green treatment solution for olive leaves utilization in a biorefinery. However, this application goes through prior optimization of technique and operating conditions. The goal of this study was to optimize the extraction of oleuropein and luteolin-7-glucoside from olive leaves through an investigation of the influence of key factors of ultrasound-assisted extraction using an experimental central composite design, in comparison with conventional Soxhlet extraction. The highest extraction efficiency and antioxidant capacity were obtained under optimal increment of temperature and amplitude conditions (40 °C and 30%, respectively). Values for oleuropein, luteolin-7-glucoside were 69.91 g/kg and 1.82 g/kg, respectively.https://www.mdpi.com/1996-1073/12/13/2486antioxidantsbioactive compoundsbiorefineryexperimental designolive leavesolive biomassresponse surface methodologyultrasound-assisted extractionolive byproducts valorization |
| spellingShingle | Antonio Lama-Muñoz María del Mar Contreras Francisco Espínola Manuel Moya Inmaculada Romero Eulogio Castro Optimization of Oleuropein and Luteolin-7-O-Glucoside Extraction from Olive Leaves by Ultrasound-Assisted Technology Energies antioxidants bioactive compounds biorefinery experimental design olive leaves olive biomass response surface methodology ultrasound-assisted extraction olive byproducts valorization |
| title | Optimization of Oleuropein and Luteolin-7-O-Glucoside Extraction from Olive Leaves by Ultrasound-Assisted Technology |
| title_full | Optimization of Oleuropein and Luteolin-7-O-Glucoside Extraction from Olive Leaves by Ultrasound-Assisted Technology |
| title_fullStr | Optimization of Oleuropein and Luteolin-7-O-Glucoside Extraction from Olive Leaves by Ultrasound-Assisted Technology |
| title_full_unstemmed | Optimization of Oleuropein and Luteolin-7-O-Glucoside Extraction from Olive Leaves by Ultrasound-Assisted Technology |
| title_short | Optimization of Oleuropein and Luteolin-7-O-Glucoside Extraction from Olive Leaves by Ultrasound-Assisted Technology |
| title_sort | optimization of oleuropein and luteolin 7 o glucoside extraction from olive leaves by ultrasound assisted technology |
| topic | antioxidants bioactive compounds biorefinery experimental design olive leaves olive biomass response surface methodology ultrasound-assisted extraction olive byproducts valorization |
| url | https://www.mdpi.com/1996-1073/12/13/2486 |
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