Nanoliposomes containing three essential oils from the Artemisia genus as effective larvicides against Aedes aegypti and Anopheles stephensi
Abstract Aedes aegypti and Anopheles stephensi have challenged human health by transmitting several infectious disease agents, such as malaria, dengue fever, and yellow fever. Larvicides, especially in endemic regions, is an effective approach to the control of mosquito-borne diseases. In this study...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-07-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-38284-6 |
| _version_ | 1797784711950499840 |
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| author | Alireza Sanei-Dehkordi Abdolmajid Ghasemian Elham Zarenezhad Hajar Qasemi Mahdi Nasiri Mahmoud Osanloo |
| author_facet | Alireza Sanei-Dehkordi Abdolmajid Ghasemian Elham Zarenezhad Hajar Qasemi Mahdi Nasiri Mahmoud Osanloo |
| author_sort | Alireza Sanei-Dehkordi |
| collection | DOAJ |
| description | Abstract Aedes aegypti and Anopheles stephensi have challenged human health by transmitting several infectious disease agents, such as malaria, dengue fever, and yellow fever. Larvicides, especially in endemic regions, is an effective approach to the control of mosquito-borne diseases. In this study, the composition of three essential oil from the Artemisia L. family was analyzed by Gas Chromatography–Mass Spectrometry. Afterward, nanoliposomes containing essential oils of A. annua, A. dracunculus, and A. sieberi with particle sizes of 137 ± 5, 151 ± 6, and 92 ± 5 nm were prepared. Besides, their zeta potential values were obtained at 32 ± 0.5, 32 ± 0.6, and 43 ± 1.7 mV. ATR-FTIR analysis (Attenuated Total Reflection-Fourier Transform InfraRed) confirmed the successful loading of the essential oils. Moreover, The LC50 values of nanoliposomes against Ae. aegypti larvae were 34, 151, and 197 µg/mL. These values for An.stephensi were obtained as 23 and 90, and 140 µg/mL, respectively. The results revealed that nanoliposomes containing A. dracunculus exerted the highest potential larvicidal effect against Ae. aegypti and An. stephensi, which can be considered against other mosquitoes. |
| first_indexed | 2024-03-13T00:43:47Z |
| format | Article |
| id | doaj.art-a0ba53e483db46828da69d0e5541dc6c |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-13T00:43:47Z |
| publishDate | 2023-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-a0ba53e483db46828da69d0e5541dc6c2023-07-09T11:11:45ZengNature PortfolioScientific Reports2045-23222023-07-0113111010.1038/s41598-023-38284-6Nanoliposomes containing three essential oils from the Artemisia genus as effective larvicides against Aedes aegypti and Anopheles stephensiAlireza Sanei-Dehkordi0Abdolmajid Ghasemian1Elham Zarenezhad2Hajar Qasemi3Mahdi Nasiri4Mahmoud Osanloo5Department of Medical Entomology and Vector Control, School of Health, Hormozgan University of Medical SciencesNoncommunicable Diseases Research Center, Fasa University of Medical SciencesNoncommunicable Diseases Research Center, Fasa University of Medical SciencesNoncommunicable Diseases Research Center, Fasa University of Medical SciencesDepartment of Medical Biotechnology, School of Advanced Technologies in Medicine, Fasa University of Medical SciencesDepartment of Medical Nanotechnology, School of Advanced Technologies in Medicine, Fasa University of Medical SciencesAbstract Aedes aegypti and Anopheles stephensi have challenged human health by transmitting several infectious disease agents, such as malaria, dengue fever, and yellow fever. Larvicides, especially in endemic regions, is an effective approach to the control of mosquito-borne diseases. In this study, the composition of three essential oil from the Artemisia L. family was analyzed by Gas Chromatography–Mass Spectrometry. Afterward, nanoliposomes containing essential oils of A. annua, A. dracunculus, and A. sieberi with particle sizes of 137 ± 5, 151 ± 6, and 92 ± 5 nm were prepared. Besides, their zeta potential values were obtained at 32 ± 0.5, 32 ± 0.6, and 43 ± 1.7 mV. ATR-FTIR analysis (Attenuated Total Reflection-Fourier Transform InfraRed) confirmed the successful loading of the essential oils. Moreover, The LC50 values of nanoliposomes against Ae. aegypti larvae were 34, 151, and 197 µg/mL. These values for An.stephensi were obtained as 23 and 90, and 140 µg/mL, respectively. The results revealed that nanoliposomes containing A. dracunculus exerted the highest potential larvicidal effect against Ae. aegypti and An. stephensi, which can be considered against other mosquitoes.https://doi.org/10.1038/s41598-023-38284-6 |
| spellingShingle | Alireza Sanei-Dehkordi Abdolmajid Ghasemian Elham Zarenezhad Hajar Qasemi Mahdi Nasiri Mahmoud Osanloo Nanoliposomes containing three essential oils from the Artemisia genus as effective larvicides against Aedes aegypti and Anopheles stephensi Scientific Reports |
| title | Nanoliposomes containing three essential oils from the Artemisia genus as effective larvicides against Aedes aegypti and Anopheles stephensi |
| title_full | Nanoliposomes containing three essential oils from the Artemisia genus as effective larvicides against Aedes aegypti and Anopheles stephensi |
| title_fullStr | Nanoliposomes containing three essential oils from the Artemisia genus as effective larvicides against Aedes aegypti and Anopheles stephensi |
| title_full_unstemmed | Nanoliposomes containing three essential oils from the Artemisia genus as effective larvicides against Aedes aegypti and Anopheles stephensi |
| title_short | Nanoliposomes containing three essential oils from the Artemisia genus as effective larvicides against Aedes aegypti and Anopheles stephensi |
| title_sort | nanoliposomes containing three essential oils from the artemisia genus as effective larvicides against aedes aegypti and anopheles stephensi |
| url | https://doi.org/10.1038/s41598-023-38284-6 |
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