Cotinine: Pharmacologically Active Metabolite of Nicotine and Neural Mechanisms for Its Actions
Tobacco use disorder continues to be a leading public health issue and cause of premature death in the United States. Nicotine is considered as the major tobacco alkaloid causing addiction through its actions on nicotinic acetylcholine receptors (nAChRs). Current pharmacotherapies targeting nicotine...
Main Authors: | Xiaoying Tan, Kent Vrana, Zheng-Ming Ding |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-10-01
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Series: | Frontiers in Behavioral Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fnbeh.2021.758252/full |
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