Nucleobase and nucleoside transport and integration into plant metabolism
Nucleotide metabolism is an essential process in all living organisms. Besides newly synthesized nucleotides, the recycling (salvage) of partially degraded nucleotides i.e. nucleosides and nucleobases serves to keep the homeostasis of the nucleotide pool. Both types of metabolites are substrates of...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2014-09-01
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| Series: | Frontiers in Plant Science |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00443/full |
| _version_ | 1811284078036516864 |
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| author | Christopher eGirke Manuel eDaumann Sandra eNiopek-Witz Torsten eMöhlmann |
| author_facet | Christopher eGirke Manuel eDaumann Sandra eNiopek-Witz Torsten eMöhlmann |
| author_sort | Christopher eGirke |
| collection | DOAJ |
| description | Nucleotide metabolism is an essential process in all living organisms. Besides newly synthesized nucleotides, the recycling (salvage) of partially degraded nucleotides i.e. nucleosides and nucleobases serves to keep the homeostasis of the nucleotide pool. Both types of metabolites are substrates of at least six families of transport proteins in Arabidopsis thaliana (Arabidopsis) with a total of 49 members. In the last years several members of such transport proteins have been analyzed allowing to present a more detailed picture of nucleoside and nucleobase transport and the physiological function of these processes. Besides functioning in nucleotide metabolism it turned out that individual members of the before named transporters exhibit the capacity to transport a wide range of different substrates including vitamins and phytohormones. The aim of this review is to summarize the current knowledge on nucleobase and nucleoside transport processes in plants and integrate this into nucleotide metabolism in general. Thereby, we will focus on those proteins which have been characterized at the biochemical level. |
| first_indexed | 2024-04-13T02:23:12Z |
| format | Article |
| id | doaj.art-a0bed929c82e47c890d97284eb1b01fd |
| institution | Directory Open Access Journal |
| issn | 1664-462X |
| language | English |
| last_indexed | 2024-04-13T02:23:12Z |
| publishDate | 2014-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj.art-a0bed929c82e47c890d97284eb1b01fd2022-12-22T03:06:53ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2014-09-01510.3389/fpls.2014.00443107646Nucleobase and nucleoside transport and integration into plant metabolismChristopher eGirke0Manuel eDaumann1Sandra eNiopek-Witz2Torsten eMöhlmann3University of KaiserslauternUniversity of KaiserslauternUniversity of KaiserslauternUniversity of KaiserslauternNucleotide metabolism is an essential process in all living organisms. Besides newly synthesized nucleotides, the recycling (salvage) of partially degraded nucleotides i.e. nucleosides and nucleobases serves to keep the homeostasis of the nucleotide pool. Both types of metabolites are substrates of at least six families of transport proteins in Arabidopsis thaliana (Arabidopsis) with a total of 49 members. In the last years several members of such transport proteins have been analyzed allowing to present a more detailed picture of nucleoside and nucleobase transport and the physiological function of these processes. Besides functioning in nucleotide metabolism it turned out that individual members of the before named transporters exhibit the capacity to transport a wide range of different substrates including vitamins and phytohormones. The aim of this review is to summarize the current knowledge on nucleobase and nucleoside transport processes in plants and integrate this into nucleotide metabolism in general. Thereby, we will focus on those proteins which have been characterized at the biochemical level.http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00443/fullAdenosineUracilUridineplant nucleotide metabolismnucleobase transportnucleoside transport |
| spellingShingle | Christopher eGirke Manuel eDaumann Sandra eNiopek-Witz Torsten eMöhlmann Nucleobase and nucleoside transport and integration into plant metabolism Frontiers in Plant Science Adenosine Uracil Uridine plant nucleotide metabolism nucleobase transport nucleoside transport |
| title | Nucleobase and nucleoside transport and integration into plant metabolism |
| title_full | Nucleobase and nucleoside transport and integration into plant metabolism |
| title_fullStr | Nucleobase and nucleoside transport and integration into plant metabolism |
| title_full_unstemmed | Nucleobase and nucleoside transport and integration into plant metabolism |
| title_short | Nucleobase and nucleoside transport and integration into plant metabolism |
| title_sort | nucleobase and nucleoside transport and integration into plant metabolism |
| topic | Adenosine Uracil Uridine plant nucleotide metabolism nucleobase transport nucleoside transport |
| url | http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00443/full |
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