A Novel Surface Modification Strategy via Photopolymerized Poly-Sulfobetaine Methacrylate Coating to Prevent Bacterial Adhesion on Titanium Surfaces
Recent investigations on the anti-adhesive properties of polysulfobetaine methacrylate (pSBMA) coatings had shown promising potential as antifouling surfaces and have given the impetus for the present paper, where a pSBMA coating is applied via photopolymerization on a macro-roughened, sandblasted,...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-06-01
|
| Series: | Materials |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1996-1944/14/12/3303 |
| _version_ | 1797530134041853952 |
|---|---|
| author | Aydin Gülses Antonia Lopar Martha Es-Souni Marie Emmert Mona Es-Souni Eleonore Behrens Hendrik Naujokat Kim Rouven Liedtke Yahya Acil Jörg Wiltfang Christian Flörke |
| author_facet | Aydin Gülses Antonia Lopar Martha Es-Souni Marie Emmert Mona Es-Souni Eleonore Behrens Hendrik Naujokat Kim Rouven Liedtke Yahya Acil Jörg Wiltfang Christian Flörke |
| author_sort | Aydin Gülses |
| collection | DOAJ |
| description | Recent investigations on the anti-adhesive properties of polysulfobetaine methacrylate (pSBMA) coatings had shown promising potential as antifouling surfaces and have given the impetus for the present paper, where a pSBMA coating is applied via photopolymerization on a macro-roughened, sandblasted, and acid-etched titanium implant surface in order to assess its antifouling properties. Current emphasis is placed on how the coating is efficient against the adhesion of Enterococcus faecalis by quantitative assessment of colony forming units and qualitative investigation of fluorescence imaging and scanning electron microscopy. pSBMA coatings via photopolymerization of titanium surfaces seems to be a promising antiadhesion strategy, which should bring substantial benefits once certain aspects such as biodegradation and osseointegration were addressed. Additionally, commercial SAL-titanium substrates may be coated with the super-hydrophilic coating, appearing resistant to physiological salt concentrations and most importantly lowering E. faecalis colonization significantly, compared to titanium substrates in the as-received state. It is very likely that pSBMA coatings may also prevent the adhesion of other germs. |
| first_indexed | 2024-03-10T10:24:38Z |
| format | Article |
| id | doaj.art-a0c295f361fe4a8789db5801c7713aab |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-10T10:24:38Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-a0c295f361fe4a8789db5801c7713aab2023-11-22T00:10:26ZengMDPI AGMaterials1996-19442021-06-011412330310.3390/ma14123303A Novel Surface Modification Strategy via Photopolymerized Poly-Sulfobetaine Methacrylate Coating to Prevent Bacterial Adhesion on Titanium SurfacesAydin Gülses0Antonia Lopar1Martha Es-Souni2Marie Emmert3Mona Es-Souni4Eleonore Behrens5Hendrik Naujokat6Kim Rouven Liedtke7Yahya Acil8Jörg Wiltfang9Christian Flörke10Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Christian-Albrecht University, UKSH, 24105 Kiel, GermanyDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine, Christian-Albrecht University, UKSH, 24105 Kiel, GermanyDepartment of Orthodontics, Faculty of Dentistry, Christian-Albrecht University, UKSH, 24105 Kiel, GermanyDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine, Christian-Albrecht University, UKSH, 24105 Kiel, GermanyDepartment of Orthodontics, Faculty of Dentistry, Christian-Albrecht University, UKSH, 24105 Kiel, GermanyDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine, Christian-Albrecht University, UKSH, 24105 Kiel, GermanyDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine, Christian-Albrecht University, UKSH, 24105 Kiel, GermanyDepartment of Orthopedics, Faculty of Medicine, Christian-Albrecht University, UKSH, 24105 Kiel, GermanyDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine, Christian-Albrecht University, UKSH, 24105 Kiel, GermanyDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine, Christian-Albrecht University, UKSH, 24105 Kiel, GermanyDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine, Christian-Albrecht University, UKSH, 24105 Kiel, GermanyRecent investigations on the anti-adhesive properties of polysulfobetaine methacrylate (pSBMA) coatings had shown promising potential as antifouling surfaces and have given the impetus for the present paper, where a pSBMA coating is applied via photopolymerization on a macro-roughened, sandblasted, and acid-etched titanium implant surface in order to assess its antifouling properties. Current emphasis is placed on how the coating is efficient against the adhesion of Enterococcus faecalis by quantitative assessment of colony forming units and qualitative investigation of fluorescence imaging and scanning electron microscopy. pSBMA coatings via photopolymerization of titanium surfaces seems to be a promising antiadhesion strategy, which should bring substantial benefits once certain aspects such as biodegradation and osseointegration were addressed. Additionally, commercial SAL-titanium substrates may be coated with the super-hydrophilic coating, appearing resistant to physiological salt concentrations and most importantly lowering E. faecalis colonization significantly, compared to titanium substrates in the as-received state. It is very likely that pSBMA coatings may also prevent the adhesion of other germs.https://www.mdpi.com/1996-1944/14/12/3303titaniumantibacterialpolysulfobetaine methacrylate |
| spellingShingle | Aydin Gülses Antonia Lopar Martha Es-Souni Marie Emmert Mona Es-Souni Eleonore Behrens Hendrik Naujokat Kim Rouven Liedtke Yahya Acil Jörg Wiltfang Christian Flörke A Novel Surface Modification Strategy via Photopolymerized Poly-Sulfobetaine Methacrylate Coating to Prevent Bacterial Adhesion on Titanium Surfaces Materials titanium antibacterial polysulfobetaine methacrylate |
| title | A Novel Surface Modification Strategy via Photopolymerized Poly-Sulfobetaine Methacrylate Coating to Prevent Bacterial Adhesion on Titanium Surfaces |
| title_full | A Novel Surface Modification Strategy via Photopolymerized Poly-Sulfobetaine Methacrylate Coating to Prevent Bacterial Adhesion on Titanium Surfaces |
| title_fullStr | A Novel Surface Modification Strategy via Photopolymerized Poly-Sulfobetaine Methacrylate Coating to Prevent Bacterial Adhesion on Titanium Surfaces |
| title_full_unstemmed | A Novel Surface Modification Strategy via Photopolymerized Poly-Sulfobetaine Methacrylate Coating to Prevent Bacterial Adhesion on Titanium Surfaces |
| title_short | A Novel Surface Modification Strategy via Photopolymerized Poly-Sulfobetaine Methacrylate Coating to Prevent Bacterial Adhesion on Titanium Surfaces |
| title_sort | novel surface modification strategy via photopolymerized poly sulfobetaine methacrylate coating to prevent bacterial adhesion on titanium surfaces |
| topic | titanium antibacterial polysulfobetaine methacrylate |
| url | https://www.mdpi.com/1996-1944/14/12/3303 |
| work_keys_str_mv | AT aydingulses anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT antonialopar anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT marthaessouni anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT marieemmert anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT monaessouni anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT eleonorebehrens anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT hendriknaujokat anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT kimrouvenliedtke anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT yahyaacil anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT jorgwiltfang anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT christianflorke anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT aydingulses novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT antonialopar novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT marthaessouni novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT marieemmert novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT monaessouni novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT eleonorebehrens novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT hendriknaujokat novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT kimrouvenliedtke novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT yahyaacil novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT jorgwiltfang novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT christianflorke novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces |