Integrins Increase Sarcoplasmic Reticulum Activity for Excitation—Contraction Coupling in Human Stem Cell-Derived Cardiomyocytes

Integrins Increase Sarcoplasmic Reticulum Activity for Excitation—Contraction Coupling in Human Stem Cell-Derived Cardiomyocytes

Engagement of the sarcoplasmic reticulum (SR) Ca<sup>2+</sup> stores for excitation–contraction (EC)-coupling is a fundamental feature of cardiac muscle cells. Extracellular matrix (ECM) proteins that form the extracellular scaffolding supporting cardiac contractile activity are thought...

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Bibliographic Details
Main Authors:	Brian X. Wang, Christopher Kane, Laura Nicastro, Oisín King, Worrapong Kit-Anan, Barrett Downing, Graziano Deidda, Liam S. Couch, Christian Pinali, Anna Mitraki, Kenneth T. MacLeod, Cesare M. Terracciano
Format:	Article
Language:	English
Published:	MDPI AG 2022-09-01
Series:	International Journal of Molecular Sciences
Subjects:	stem cell integrin Ca<sup>2+</sup> cycling cardiomyocyte fibrosis sarcoplasmic reticulum
Online Access:	https://www.mdpi.com/1422-0067/23/18/10940

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