Eczema herpeticum and impetigo herpetiformis, is there a link?

Abstract Impetigo herpetiformis (IH) is a rare variant of pustular psoriasis with typical onset during the third trimester of pregnancy; it is characterized by erythematous plaques lined with sterile pustules and sometimes there may be systemic involvement. On the other hand, eczema herpeticum (EH)...

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Main Authors: Fortunato Cassalia, Jacopo Tartaglia, Davide Zardo, Francesca Caroppo, Anna Belloni Fortina
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:JEADV Clinical Practice
Subjects:
Online Access:https://doi.org/10.1002/jvc2.79
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author Fortunato Cassalia
Jacopo Tartaglia
Davide Zardo
Francesca Caroppo
Anna Belloni Fortina
author_facet Fortunato Cassalia
Jacopo Tartaglia
Davide Zardo
Francesca Caroppo
Anna Belloni Fortina
author_sort Fortunato Cassalia
collection DOAJ
description Abstract Impetigo herpetiformis (IH) is a rare variant of pustular psoriasis with typical onset during the third trimester of pregnancy; it is characterized by erythematous plaques lined with sterile pustules and sometimes there may be systemic involvement. On the other hand, eczema herpeticum (EH) is defined as a disseminated skin infection by herpes simplex virus type 1, which mainly affects patients characterized by an impaired integrity of the skin barrier, mostly atopic dermatitis. We report the case of a 30‐year‐old woman, primigravida at 28 + 3 weeks of gestation, who after asymptomatic severe acute respiratory syndrome coronavirus 2 infection for about 7 days presented to the emergency room with a burning and itching rash on the trunk and limbs. She reported a long‐standing history of atopic dermatitis and recurrent herpetic eruptions. The diagnosis of EH was made and systemic therapy was set with excellent results. A few days later, the patient developed a pustular rash in the areas previously affected by EH, with histologic features of IH. A relation between EH and IH is thus suggested.
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spelling doaj.art-a0c4aff27fd84bddbfc466b60a60130f2023-03-01T09:59:22ZengWileyJEADV Clinical Practice2768-65662023-03-012114014310.1002/jvc2.79Eczema herpeticum and impetigo herpetiformis, is there a link?Fortunato Cassalia0Jacopo Tartaglia1Davide Zardo2Francesca Caroppo3Anna Belloni Fortina4Unit of Dermatology, Department of Medicine University of Padova Padua ItalyUnit of Dermatology, Department of Medicine University of Padova Padua ItalySurgical Pathology and Cytopathology Unit San Bortolo Hospital Vicenza ItalyUnit of Dermatology, Department of Medicine University of Padova Padua ItalyUnit of Dermatology, Department of Medicine University of Padova Padua ItalyAbstract Impetigo herpetiformis (IH) is a rare variant of pustular psoriasis with typical onset during the third trimester of pregnancy; it is characterized by erythematous plaques lined with sterile pustules and sometimes there may be systemic involvement. On the other hand, eczema herpeticum (EH) is defined as a disseminated skin infection by herpes simplex virus type 1, which mainly affects patients characterized by an impaired integrity of the skin barrier, mostly atopic dermatitis. We report the case of a 30‐year‐old woman, primigravida at 28 + 3 weeks of gestation, who after asymptomatic severe acute respiratory syndrome coronavirus 2 infection for about 7 days presented to the emergency room with a burning and itching rash on the trunk and limbs. She reported a long‐standing history of atopic dermatitis and recurrent herpetic eruptions. The diagnosis of EH was made and systemic therapy was set with excellent results. A few days later, the patient developed a pustular rash in the areas previously affected by EH, with histologic features of IH. A relation between EH and IH is thus suggested.https://doi.org/10.1002/jvc2.79eczema herpeticumimpetigo herpetiformisKoebner's phenomenonWolf's isotopic response
spellingShingle Fortunato Cassalia
Jacopo Tartaglia
Davide Zardo
Francesca Caroppo
Anna Belloni Fortina
Eczema herpeticum and impetigo herpetiformis, is there a link?
JEADV Clinical Practice
eczema herpeticum
impetigo herpetiformis
Koebner's phenomenon
Wolf's isotopic response
title Eczema herpeticum and impetigo herpetiformis, is there a link?
title_full Eczema herpeticum and impetigo herpetiformis, is there a link?
title_fullStr Eczema herpeticum and impetigo herpetiformis, is there a link?
title_full_unstemmed Eczema herpeticum and impetigo herpetiformis, is there a link?
title_short Eczema herpeticum and impetigo herpetiformis, is there a link?
title_sort eczema herpeticum and impetigo herpetiformis is there a link
topic eczema herpeticum
impetigo herpetiformis
Koebner's phenomenon
Wolf's isotopic response
url https://doi.org/10.1002/jvc2.79
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