ABCA1 transporter promotes the motility of human melanoma cells by modulating their plasma membrane organization

ABCA1 transporter promotes the motility of human melanoma cells by modulating their plasma membrane organization

Abstract Background Melanoma is one of the most aggressive and deadliest skin tumor. Cholesterol content in melanoma cells is elevated, and a portion of it accumulates into lipid rafts. Therefore, the plasma membrane cholesterol and its lateral organization might be directly linked with tumor develo...

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Bibliographic Details
Main Authors: Ambroise Wu, Ewa Mazurkiewicz, Piotr Donizy, Krzysztof Kotowski, Małgorzata Pieniazek, Antonina J. Mazur, Aleksander Czogalla, Tomasz Trombik
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Biological Research
Subjects:
ABCA1
Cell motility
Cholesterol
Human melanoma
Plasma membrane
Online Access:https://doi.org/10.1186/s40659-023-00443-4

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