Laser-induced autofluorescence for assessment of methabolism and hemodynamic characteristics of the brain
The paper contains results of the investigation of the laser-inducedfluorescence detection method for the assessment ofbrain metabolism in situ through the dura mater. Models ofanoxia and acute brain ischemia were used for the evaluation ofreliability of the method utilizing registration of reduced...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Research Center of Neurology
2017-02-01
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| Series: | Анналы клинической и экспериментальной неврологии |
| Subjects: | |
| Online Access: | https://annaly-nevrologii.com/journal/pathID/article/viewFile/299/201 |
| _version_ | 1828728820487684096 |
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| author | A. B. Salmina V. V. Salmin O. V. Frolova D. I. Laletin M. A. Fursov D. P. Skomorokha A. A. Fursov M. A. Kondrashov N. N. Medvedeva N. A. Malinovskaya N. S. Mantorova |
| author_facet | A. B. Salmina V. V. Salmin O. V. Frolova D. I. Laletin M. A. Fursov D. P. Skomorokha A. A. Fursov M. A. Kondrashov N. N. Medvedeva N. A. Malinovskaya N. S. Mantorova |
| author_sort | A. B. Salmina |
| collection | DOAJ |
| description | The paper contains results of the investigation of the laser-inducedfluorescence detection method for the assessment ofbrain metabolism in situ through the dura mater. Models ofanoxia and acute brain ischemia were used for the evaluation ofreliability of the method utilizing registration of reduced tissuepyridine nucleotides fluorescence, as well as for the assessmentof the viability index, based on the conversion of oxy- anddeoxyhemoglobin. Some pathobiochemical mechanisms ofalterations in the pool ofpyridine nucleotides in anoxia and ischemia were analyzed. |
| first_indexed | 2024-04-12T14:22:08Z |
| format | Article |
| id | doaj.art-a0c69751938d48e9b675d9d420ab45c7 |
| institution | Directory Open Access Journal |
| issn | 2075-5473 2409-2533 |
| language | English |
| last_indexed | 2024-04-12T14:22:08Z |
| publishDate | 2017-02-01 |
| publisher | Research Center of Neurology |
| record_format | Article |
| series | Анналы клинической и экспериментальной неврологии |
| spelling | doaj.art-a0c69751938d48e9b675d9d420ab45c72022-12-22T03:29:32ZengResearch Center of NeurologyАнналы клинической и экспериментальной неврологии2075-54732409-25332017-02-0153323910.17816/psaic299202Laser-induced autofluorescence for assessment of methabolism and hemodynamic characteristics of the brainA. B. Salmina0V. V. Salmin1O. V. Frolova2D. I. Laletin3M. A. Fursov4D. P. Skomorokha5A. A. Fursov6M. A. Kondrashov7N. N. Medvedeva8N. A. Malinovskaya9N. S. Mantorova10Department of Biochemistry, Medical, Pharmaceutical and Toxicological ChemistryDepartment of Photonics and Laser Technologies, IEPRE, Siberian Federal University (Krasnoyarsk)Department of Histology and Embryology Krasnoyarsk State Medical University named after Prof. V.F.Voino-YasenetskyDepartment of Histology and Embryology Krasnoyarsk State Medical University named after Prof. V.F.Voino-YasenetskyDepartment of Histology and Embryology Krasnoyarsk State Medical University named after Prof. V.F.Voino-YasenetskyDepartment of Photonics and Laser Technologies, IEPRE, Siberian Federal University (Krasnoyarsk)Department of Histology and Embryology Krasnoyarsk State Medical University named after Prof. V.F.Voino-YasenetskyDepartment of Histology and Embryology Krasnoyarsk State Medical University named after Prof. V.F.Voino-YasenetskyDepartment of Histology and Embryology Krasnoyarsk State Medical University named after Prof. V.F.Voino-YasenetskyDepartment of Histology and Embryology Krasnoyarsk State Medical University named after Prof. V.F.Voino-YasenetskyDepartment of Histology and Embryology Krasnoyarsk State Medical University named after Prof. V.F.Voino-YasenetskyThe paper contains results of the investigation of the laser-inducedfluorescence detection method for the assessment ofbrain metabolism in situ through the dura mater. Models ofanoxia and acute brain ischemia were used for the evaluation ofreliability of the method utilizing registration of reduced tissuepyridine nucleotides fluorescence, as well as for the assessmentof the viability index, based on the conversion of oxy- anddeoxyhemoglobin. Some pathobiochemical mechanisms ofalterations in the pool ofpyridine nucleotides in anoxia and ischemia were analyzed.https://annaly-nevrologii.com/journal/pathID/article/viewFile/299/201brainautofluorescencepyridine nucleotides |
| spellingShingle | A. B. Salmina V. V. Salmin O. V. Frolova D. I. Laletin M. A. Fursov D. P. Skomorokha A. A. Fursov M. A. Kondrashov N. N. Medvedeva N. A. Malinovskaya N. S. Mantorova Laser-induced autofluorescence for assessment of methabolism and hemodynamic characteristics of the brain Анналы клинической и экспериментальной неврологии brain autofluorescence pyridine nucleotides |
| title | Laser-induced autofluorescence for assessment of methabolism and hemodynamic characteristics of the brain |
| title_full | Laser-induced autofluorescence for assessment of methabolism and hemodynamic characteristics of the brain |
| title_fullStr | Laser-induced autofluorescence for assessment of methabolism and hemodynamic characteristics of the brain |
| title_full_unstemmed | Laser-induced autofluorescence for assessment of methabolism and hemodynamic characteristics of the brain |
| title_short | Laser-induced autofluorescence for assessment of methabolism and hemodynamic characteristics of the brain |
| title_sort | laser induced autofluorescence for assessment of methabolism and hemodynamic characteristics of the brain |
| topic | brain autofluorescence pyridine nucleotides |
| url | https://annaly-nevrologii.com/journal/pathID/article/viewFile/299/201 |
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