Dynamics and consequences of spliceosome E complex formation

Dynamics and consequences of spliceosome E complex formation

The spliceosome must identify the correct splice sites (SS) and branchsite (BS) used during splicing. E complex is the earliest spliceosome precursor in which the 5' SS and BS are defined. Definition occurs by U1 small nuclear ribonucleoprotein (snRNP) binding the 5' SS and recognition of...

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Bibliographic Details
Main Authors: Joshua Donald Larson, Aaron A Hoskins
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-08-01
Series:eLife
Subjects:
splicing
single molecule fluorescence
CoSMoS
spliceosome
snRNP
RNA
Online Access:https://elifesciences.org/articles/27592

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