Co-occurrence of Wilson disease and Auto-Immune Hepatitis in 14-year-old female: A case report

Unusual cases of coexistence between Wilson's disease and autoimmune hepatitis have occurred. There are characteristics of both diseases in this community of patients, and laboratory and histo pathological findings can be misleading. Wilson disease's clinical appearance can differ widely;...

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Main Authors: Fadwa Ghassan Hameed, Inam Sameh Arif, Mohammed Mahmood Mohammed, Hala S. Arif
Format: Article
Language:English
Published: College of Pharmacy / Mustansiriyah University 2022-04-01
Series:Al-Mustansiriyah Journal of Pharmaceutical Sciences
Subjects:
Online Access:https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/803
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author Fadwa Ghassan Hameed
Inam Sameh Arif
Mohammed Mahmood Mohammed
Hala S. Arif
author_facet Fadwa Ghassan Hameed
Inam Sameh Arif
Mohammed Mahmood Mohammed
Hala S. Arif
author_sort Fadwa Ghassan Hameed
collection DOAJ
description Unusual cases of coexistence between Wilson's disease and autoimmune hepatitis have occurred. There are characteristics of both diseases in this community of patients, and laboratory and histo pathological findings can be misleading. Wilson disease's clinical appearance can differ widely; thus, there is not always an easy diagnosis. In addition to being childhood and young adult illnesses, Wilson's disease can also be triggered at any age. Liver disease and cirrhosis, neuropsychiatric disorders, Kayser-Fleischer(KF.) rings, and acute hemolysis events are the primary characteristics of Wilson's disease, frequently in combination with acute liver failure. Diagnosis is extremely difficult for children and adults with active liver disease. None of the latest Wilson's disease laboratory tests are optimal and may not be specific. Therefore, by taking into account acute hepatitis similar to Wilson's disease and autoimmune hepatitis, concomitant treatment with immunosuppression and penicillamine may have a superior impact.
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spelling doaj.art-a0cba00c62b94427b8a9365216065fb02024-04-04T06:56:28ZengCollege of Pharmacy / Mustansiriyah UniversityAl-Mustansiriyah Journal of Pharmaceutical Sciences1815-09932959-183X2022-04-0121210.32947/ajps.v21i2.803Co-occurrence of Wilson disease and Auto-Immune Hepatitis in 14-year-old female: A case reportFadwa Ghassan Hameed0Inam Sameh Arif1Mohammed Mahmood Mohammed2Hala S. Arif 3Department of Pharmacy, Al-Kitab University, Kirkuk, Iraq. Department of Pharmacology and Toxicology, College of Pharmacy, University of Al-Mustanseriah, Baghdad, Iraq.Department of Clinical Pharmacy, College of Pharmacy, University of Al-Mustanseriah, Baghdad, IraqDepartment Pediatric, College of Medicine, Al-Nahrain University, Baghdad, Iraq.*University, Baghdad, Iraq Unusual cases of coexistence between Wilson's disease and autoimmune hepatitis have occurred. There are characteristics of both diseases in this community of patients, and laboratory and histo pathological findings can be misleading. Wilson disease's clinical appearance can differ widely; thus, there is not always an easy diagnosis. In addition to being childhood and young adult illnesses, Wilson's disease can also be triggered at any age. Liver disease and cirrhosis, neuropsychiatric disorders, Kayser-Fleischer(KF.) rings, and acute hemolysis events are the primary characteristics of Wilson's disease, frequently in combination with acute liver failure. Diagnosis is extremely difficult for children and adults with active liver disease. None of the latest Wilson's disease laboratory tests are optimal and may not be specific. Therefore, by taking into account acute hepatitis similar to Wilson's disease and autoimmune hepatitis, concomitant treatment with immunosuppression and penicillamine may have a superior impact. https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/803Autoimmune liver disease, Histopathology, Wilson’s disease, Kayser–Fleischer rings.
spellingShingle Fadwa Ghassan Hameed
Inam Sameh Arif
Mohammed Mahmood Mohammed
Hala S. Arif
Co-occurrence of Wilson disease and Auto-Immune Hepatitis in 14-year-old female: A case report
Al-Mustansiriyah Journal of Pharmaceutical Sciences
Autoimmune liver disease, Histopathology, Wilson’s disease, Kayser–Fleischer rings.
title Co-occurrence of Wilson disease and Auto-Immune Hepatitis in 14-year-old female: A case report
title_full Co-occurrence of Wilson disease and Auto-Immune Hepatitis in 14-year-old female: A case report
title_fullStr Co-occurrence of Wilson disease and Auto-Immune Hepatitis in 14-year-old female: A case report
title_full_unstemmed Co-occurrence of Wilson disease and Auto-Immune Hepatitis in 14-year-old female: A case report
title_short Co-occurrence of Wilson disease and Auto-Immune Hepatitis in 14-year-old female: A case report
title_sort co occurrence of wilson disease and auto immune hepatitis in 14 year old female a case report
topic Autoimmune liver disease, Histopathology, Wilson’s disease, Kayser–Fleischer rings.
url https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/803
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