The treatment of acute promyelocytic leukemia in 2023: Paradigm, advances, and future directions

The treatment of acute promyelocytic leukemia in 2023: Paradigm, advances, and future directions

The transformation of acute promyelocytic leukemia (APL) from an often fatal to highly curable cancer with long-term survival exceeding 90% is one of the greatest and most inspiring successes in oncology. A deeper understanding of the pathogenesis of APL heralded the introduction of highly effective...

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Bibliographic Details
Main Authors:	Sunil Girish Iyer, Laila Elias, Michele Stanchina, Justin Watts
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Series:	Frontiers in Oncology
Subjects:	acute promyelocytic leukemia all-trans retinoic acid (ATRA) arsenic trioxide (ATO) differentiation syndrome disseminated intravascular coagulation (DIC) coagulopathy
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2022.1062524/full

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