Doxycycline monotherapy for pyoderma vegetans: a case report
Background: Pyoderma vegetans (PV) is a rare neutrophilic dermatosis of unknown etiology. Currently, there are no treatment guidelines for PV. Systemic steroids are often used as first-line therapy, but recurrence upon discontinuation or tapering is common.Materials and methods: We tested the effica...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2024-12-01
|
| Series: | Journal of Dermatological Treatment |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/09546634.2024.2329248 |
| _version_ | 1826930855328612352 |
|---|---|
| author | Jihane Belcadi Sara Oulad Ali Fatima-Zahra Sassine Mariame Meziane Karima Senouci |
| author_facet | Jihane Belcadi Sara Oulad Ali Fatima-Zahra Sassine Mariame Meziane Karima Senouci |
| author_sort | Jihane Belcadi |
| collection | DOAJ |
| description | Background: Pyoderma vegetans (PV) is a rare neutrophilic dermatosis of unknown etiology. Currently, there are no treatment guidelines for PV. Systemic steroids are often used as first-line therapy, but recurrence upon discontinuation or tapering is common.Materials and methods: We tested the efficacy of doxycycline at a dose of 200 mg/d to treat resistant PV.Results: After 4 weeks of treatment we noticed a significant improvement in the clinical appearance of PV.Conclusions: Our case demonstrates the potential utility of doxycycline as a systemic steroid-sparing agent in the treatment of PV. |
| first_indexed | 2024-04-25T00:08:18Z |
| format | Article |
| id | doaj.art-a0d02319120043eab3d4f8ac5919d133 |
| institution | Directory Open Access Journal |
| issn | 0954-6634 1471-1753 |
| language | English |
| last_indexed | 2025-02-17T16:35:17Z |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Dermatological Treatment |
| spelling | doaj.art-a0d02319120043eab3d4f8ac5919d1332024-12-16T22:53:47ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532024-12-0135110.1080/09546634.2024.2329248Doxycycline monotherapy for pyoderma vegetans: a case reportJihane Belcadi0Sara Oulad Ali1Fatima-Zahra Sassine2Mariame Meziane3Karima Senouci4Department of Dermatology, Mohamed V University of Rabat, Ibn Sina University Hospital, Rabat, MoroccoDepartment of Dermatology, Mohamed V University of Rabat, Ibn Sina University Hospital, Rabat, MoroccoDepartment of Dermatology, Mohamed V University of Rabat, Ibn Sina University Hospital, Rabat, MoroccoDepartment of Dermatology, Mohamed V University of Rabat, Ibn Sina University Hospital, Rabat, MoroccoDepartment of Dermatology, Mohamed V University of Rabat, Ibn Sina University Hospital, Rabat, MoroccoBackground: Pyoderma vegetans (PV) is a rare neutrophilic dermatosis of unknown etiology. Currently, there are no treatment guidelines for PV. Systemic steroids are often used as first-line therapy, but recurrence upon discontinuation or tapering is common.Materials and methods: We tested the efficacy of doxycycline at a dose of 200 mg/d to treat resistant PV.Results: After 4 weeks of treatment we noticed a significant improvement in the clinical appearance of PV.Conclusions: Our case demonstrates the potential utility of doxycycline as a systemic steroid-sparing agent in the treatment of PV.https://www.tandfonline.com/doi/10.1080/09546634.2024.2329248Neutrophilic dermatosispyoderma vegetansdoxycyclinesystemic steroid-sparing agent |
| spellingShingle | Jihane Belcadi Sara Oulad Ali Fatima-Zahra Sassine Mariame Meziane Karima Senouci Doxycycline monotherapy for pyoderma vegetans: a case report Journal of Dermatological Treatment Neutrophilic dermatosis pyoderma vegetans doxycycline systemic steroid-sparing agent |
| title | Doxycycline monotherapy for pyoderma vegetans: a case report |
| title_full | Doxycycline monotherapy for pyoderma vegetans: a case report |
| title_fullStr | Doxycycline monotherapy for pyoderma vegetans: a case report |
| title_full_unstemmed | Doxycycline monotherapy for pyoderma vegetans: a case report |
| title_short | Doxycycline monotherapy for pyoderma vegetans: a case report |
| title_sort | doxycycline monotherapy for pyoderma vegetans a case report |
| topic | Neutrophilic dermatosis pyoderma vegetans doxycycline systemic steroid-sparing agent |
| url | https://www.tandfonline.com/doi/10.1080/09546634.2024.2329248 |
| work_keys_str_mv | AT jihanebelcadi doxycyclinemonotherapyforpyodermavegetansacasereport AT saraouladali doxycyclinemonotherapyforpyodermavegetansacasereport AT fatimazahrasassine doxycyclinemonotherapyforpyodermavegetansacasereport AT mariamemeziane doxycyclinemonotherapyforpyodermavegetansacasereport AT karimasenouci doxycyclinemonotherapyforpyodermavegetansacasereport |