Clinical outcome of bronchoalveolar lavaged COVID ARDS patients
Introduction: One of the biggest pandemics of the human race, Coronavirus disease, has reported mortality rates as high as 80% for critically ill patients. It has killed more than 3.9 million people worldwide with no strongly proven management options to decrease its mortality. One of the options ga...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-01-01
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| Series: | Respiratory Medicine Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007122000557 |
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| author | Zablon Mesfin Anbessie Dawit Kebede Huluka Zelalem Abdisa Kenea |
| author_facet | Zablon Mesfin Anbessie Dawit Kebede Huluka Zelalem Abdisa Kenea |
| author_sort | Zablon Mesfin Anbessie |
| collection | DOAJ |
| description | Introduction: One of the biggest pandemics of the human race, Coronavirus disease, has reported mortality rates as high as 80% for critically ill patients. It has killed more than 3.9 million people worldwide with no strongly proven management options to decrease its mortality. One of the options gaining interest is fiberoptic bronchoscopy and bronchoalveolar lavage. Our study was conducted to assess the clinical outcome of intubated Coronavirus disease patients that had a fiberoptic bronchoscopy and bronchoalveolar lavage done. Methods and materials: A consecutive prospective case series of intubated patients with critical Coronavirus disease pneumonia were conducted at Bethzatha general hospital from April 20, 2021, to July 30, 2021 GC. Results: Five patients with a median age of 55 years were included in the study. The median APACHE II11 Acute physiology and chronic health evaluation., SAPS II22 Simplified acute physiology score., and SOFA33 Sequential organ failure assessment. scores on admission were 13, 37, and 4 respectively. The difference in the mean values of; positive end-expiratory pressure, static compliance, plateau pressure, fractional inspired oxygen, and arterial oxygen tension to fractional inspired oxygen ratio between the time of intubation and the last fiberoptic bronchoscopy and bronchoalveolar lavage were 4.4 cmH2O, 11 ml/cmH2O, 6.2 cmH2O, 45%, and 76 mmHg. All patients were liberated from mechanical ventilation. Conclusion: – There was a numerically and clinically significant improvement in lung mechanics and oxygenation leading to a 100% ventilator liberation rate. Fiberoptic bronchoscopy and bronchoalveolar lavage in Coronavirus disease patients can improve lung mechanics, oxygenation, and rates of extubation. |
| first_indexed | 2024-12-12T04:37:09Z |
| format | Article |
| id | doaj.art-a0d85a96f755439db9b76be6dc861762 |
| institution | Directory Open Access Journal |
| issn | 2213-0071 |
| language | English |
| last_indexed | 2024-12-12T04:37:09Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj.art-a0d85a96f755439db9b76be6dc8617622022-12-22T00:37:55ZengElsevierRespiratory Medicine Case Reports2213-00712022-01-0137101633Clinical outcome of bronchoalveolar lavaged COVID ARDS patientsZablon Mesfin Anbessie0Dawit Kebede Huluka1Zelalem Abdisa Kenea2Bethzatha General Hospital, Addis Ababa, Ethiopia; Corresponding author. PO BOX-57060, Addis Ababa, Ethiopia.College of Health Sciences, Addis Ababa University, Addis Ababa, EthiopiaBethzatha General Hospital, Addis Ababa, EthiopiaIntroduction: One of the biggest pandemics of the human race, Coronavirus disease, has reported mortality rates as high as 80% for critically ill patients. It has killed more than 3.9 million people worldwide with no strongly proven management options to decrease its mortality. One of the options gaining interest is fiberoptic bronchoscopy and bronchoalveolar lavage. Our study was conducted to assess the clinical outcome of intubated Coronavirus disease patients that had a fiberoptic bronchoscopy and bronchoalveolar lavage done. Methods and materials: A consecutive prospective case series of intubated patients with critical Coronavirus disease pneumonia were conducted at Bethzatha general hospital from April 20, 2021, to July 30, 2021 GC. Results: Five patients with a median age of 55 years were included in the study. The median APACHE II11 Acute physiology and chronic health evaluation., SAPS II22 Simplified acute physiology score., and SOFA33 Sequential organ failure assessment. scores on admission were 13, 37, and 4 respectively. The difference in the mean values of; positive end-expiratory pressure, static compliance, plateau pressure, fractional inspired oxygen, and arterial oxygen tension to fractional inspired oxygen ratio between the time of intubation and the last fiberoptic bronchoscopy and bronchoalveolar lavage were 4.4 cmH2O, 11 ml/cmH2O, 6.2 cmH2O, 45%, and 76 mmHg. All patients were liberated from mechanical ventilation. Conclusion: – There was a numerically and clinically significant improvement in lung mechanics and oxygenation leading to a 100% ventilator liberation rate. Fiberoptic bronchoscopy and bronchoalveolar lavage in Coronavirus disease patients can improve lung mechanics, oxygenation, and rates of extubation.http://www.sciencedirect.com/science/article/pii/S2213007122000557BronchoscopyBronchoalveolar lavageCOVIDLung mechanicsOxygenationExtubation |
| spellingShingle | Zablon Mesfin Anbessie Dawit Kebede Huluka Zelalem Abdisa Kenea Clinical outcome of bronchoalveolar lavaged COVID ARDS patients Respiratory Medicine Case Reports Bronchoscopy Bronchoalveolar lavage COVID Lung mechanics Oxygenation Extubation |
| title | Clinical outcome of bronchoalveolar lavaged COVID ARDS patients |
| title_full | Clinical outcome of bronchoalveolar lavaged COVID ARDS patients |
| title_fullStr | Clinical outcome of bronchoalveolar lavaged COVID ARDS patients |
| title_full_unstemmed | Clinical outcome of bronchoalveolar lavaged COVID ARDS patients |
| title_short | Clinical outcome of bronchoalveolar lavaged COVID ARDS patients |
| title_sort | clinical outcome of bronchoalveolar lavaged covid ards patients |
| topic | Bronchoscopy Bronchoalveolar lavage COVID Lung mechanics Oxygenation Extubation |
| url | http://www.sciencedirect.com/science/article/pii/S2213007122000557 |
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