Hypertension is associated with osteoporosis: a case-control study in Chinese postmenopausal women
Abstract Background Osteoporosis and cardiovascular disease (CVD) are age-related diseases. It is reported that patients with CVD have a higher risk of bone loss. This retrospective study sought to reveal the association between osteoporosis and CVD in Chinese women. Although epidemiological evidenc...
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| Format: | Article |
| Language: | English |
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BMC
2021-03-01
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| Series: | BMC Musculoskeletal Disorders |
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| Online Access: | https://doi.org/10.1186/s12891-021-04124-9 |
| _version_ | 1818557967902965760 |
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| author | Hao Chai Jirong Ge Li Li Jianyang Li Yunjin Ye |
| author_facet | Hao Chai Jirong Ge Li Li Jianyang Li Yunjin Ye |
| author_sort | Hao Chai |
| collection | DOAJ |
| description | Abstract Background Osteoporosis and cardiovascular disease (CVD) are age-related diseases. It is reported that patients with CVD have a higher risk of bone loss. This retrospective study sought to reveal the association between osteoporosis and CVD in Chinese women. Although epidemiological evidence has indicated a relationship between the two, clinical data in southeast China are lacking. Methods In total, 2873 participants completed the baseline survey from January 2007 to October 2019, and 2039 were included in this retrospective study. We divided all subjects into an osteoporosis group and a non-osteoporosis group based on their bone mineral density (BMD). Dual-energy X-ray absorptiometry (DXA) was used to examine BMD. The general information came from the questionnaire survey. Cardiovascular diseases were defined by asking participants at the first visit and checking relevant medical records if they had suffered from hypertension, coronary heart disease, or cerebral infarction. Results According to the criterion, the osteoporosis group had 678 subjects, and the non-osteoporosis group had 1361 subjects. Subjects in the osteoporosis group had a significantly higher prevalence of hypertension and coronary heart disease. Besides, the proportion of subjects who drank tea and drank milk were relatively higher in the osteoporosis group. The odds ratio (OR) for suffering from osteoporosis was high if the patients had hypertension. Conclusions This study indicated that Chinese postmenopausal women with osteoporosis had a higher prevalence of hypertension. Hypertension was significantly associated with osteoporosis. |
| first_indexed | 2024-12-14T00:06:39Z |
| format | Article |
| id | doaj.art-a0dae9adc2fc40048e53e439f8dbacd1 |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-12-14T00:06:39Z |
| publishDate | 2021-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-a0dae9adc2fc40048e53e439f8dbacd12022-12-21T23:26:00ZengBMCBMC Musculoskeletal Disorders1471-24742021-03-012211710.1186/s12891-021-04124-9Hypertension is associated with osteoporosis: a case-control study in Chinese postmenopausal womenHao Chai0Jirong Ge1Li Li2Jianyang Li3Yunjin Ye4Fujian University of Traditional Chinese MedicineKey Research Laboratory of Osteoporosis Syndrome Genomics, Fujian Academy of Chinese Medical SciencesFujian University of Traditional Chinese MedicineFujian University of Traditional Chinese MedicineKey Research Laboratory of Osteoporosis Syndrome Genomics, Fujian Academy of Chinese Medical SciencesAbstract Background Osteoporosis and cardiovascular disease (CVD) are age-related diseases. It is reported that patients with CVD have a higher risk of bone loss. This retrospective study sought to reveal the association between osteoporosis and CVD in Chinese women. Although epidemiological evidence has indicated a relationship between the two, clinical data in southeast China are lacking. Methods In total, 2873 participants completed the baseline survey from January 2007 to October 2019, and 2039 were included in this retrospective study. We divided all subjects into an osteoporosis group and a non-osteoporosis group based on their bone mineral density (BMD). Dual-energy X-ray absorptiometry (DXA) was used to examine BMD. The general information came from the questionnaire survey. Cardiovascular diseases were defined by asking participants at the first visit and checking relevant medical records if they had suffered from hypertension, coronary heart disease, or cerebral infarction. Results According to the criterion, the osteoporosis group had 678 subjects, and the non-osteoporosis group had 1361 subjects. Subjects in the osteoporosis group had a significantly higher prevalence of hypertension and coronary heart disease. Besides, the proportion of subjects who drank tea and drank milk were relatively higher in the osteoporosis group. The odds ratio (OR) for suffering from osteoporosis was high if the patients had hypertension. Conclusions This study indicated that Chinese postmenopausal women with osteoporosis had a higher prevalence of hypertension. Hypertension was significantly associated with osteoporosis.https://doi.org/10.1186/s12891-021-04124-9OsteoporosisHypertensionCardiovascular diseaseBone mineral densityAssociation |
| spellingShingle | Hao Chai Jirong Ge Li Li Jianyang Li Yunjin Ye Hypertension is associated with osteoporosis: a case-control study in Chinese postmenopausal women BMC Musculoskeletal Disorders Osteoporosis Hypertension Cardiovascular disease Bone mineral density Association |
| title | Hypertension is associated with osteoporosis: a case-control study in Chinese postmenopausal women |
| title_full | Hypertension is associated with osteoporosis: a case-control study in Chinese postmenopausal women |
| title_fullStr | Hypertension is associated with osteoporosis: a case-control study in Chinese postmenopausal women |
| title_full_unstemmed | Hypertension is associated with osteoporosis: a case-control study in Chinese postmenopausal women |
| title_short | Hypertension is associated with osteoporosis: a case-control study in Chinese postmenopausal women |
| title_sort | hypertension is associated with osteoporosis a case control study in chinese postmenopausal women |
| topic | Osteoporosis Hypertension Cardiovascular disease Bone mineral density Association |
| url | https://doi.org/10.1186/s12891-021-04124-9 |
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