Structure Elucidation and Anticancer Activity of 7-Oxostaurosporine Derivatives from the Brazilian Endemic Tunicate Eudistoma vannamei

Structure Elucidation and Anticancer Activity of 7-Oxostaurosporine Derivatives from the Brazilian Endemic Tunicate Eudistoma vannamei

The present study reports the identification of two new staurosporine derivatives, 2-hydroxy-7-oxostaurosporine (<strong>1</strong>) and 3-hydroxy-7-oxostaurosporine (<strong>2</strong>), obtained from mid-polar fractions of an aqueous methanol...

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Bibliographic Details
Main Authors: Leticia Veras Costa-Lotufo, Norberto Peporine Lopes, Edilberto Rocha Silveira, Tito Monteiro da Cruz Lotufo, Renata Takeara, Manoel Odorico de Moraes, Elthon Gois Ferreira, Diego Veras Wilke, Paula Christine Jimenez
Format: Article
Language:English
Published: MDPI AG 2012-05-01
Series:Marine Drugs
Subjects:
cell cycle arrest
ascidians
staurosporine
Online Access:http://www.mdpi.com/1660-3397/10/5/1092

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