Effect of intraosseous introduction of selenium/arabinogalactan nanoglycoconjugate on the main indicators of primary metabolism in consolidation of bone fracture
The research was carried out on 9 rabbits (males) of Chinchilla breed with modeling of standard perforating fracture of femoral bone. We performed intraosseous introduction of nanocomposite elemental selenium and heteropolysaccharide arabinogalactan 50 mg Se/kg to individuals of experimental group (...
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| Format: | Article |
| Language: | Russian |
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Scientific Сentre for Family Health and Human Reproduction Problems
2016-07-01
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| Series: | Acta Biomedica Scientifica |
| Subjects: | |
| Online Access: | https://www.actabiomedica.ru/jour/article/view/251 |
| _version_ | 1797237423267119104 |
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| author | L. V. Rodionova I. A. Shurygina L. G. Samoylova B. G. Sukhov M. G. Shurygin |
| author_facet | L. V. Rodionova I. A. Shurygina L. G. Samoylova B. G. Sukhov M. G. Shurygin |
| author_sort | L. V. Rodionova |
| collection | DOAJ |
| description | The research was carried out on 9 rabbits (males) of Chinchilla breed with modeling of standard perforating fracture of femoral bone. We performed intraosseous introduction of nanocomposite elemental selenium and heteropolysaccharide arabinogalactan 50 mg Se/kg to individuals of experimental group (n = 3) and NaCl 0,9 % to individuals of control group (n = 6). It was established that local intraosseous introduction of the nanocomposite with perforated fracture model did not affect basal metabolic indicators (body temperature, oxygen consumption, carbon dioxide production), but boosted the metabolic processes in the area of the surgical wound from the 9th to 21st days. It proves the bioavailability of the drug and the possibility of creating a local depot of selenium using a nanocomposite. |
| first_indexed | 2024-03-08T12:19:07Z |
| format | Article |
| id | doaj.art-a0e1fdbbcb1141ea99650aa4b78bcac2 |
| institution | Directory Open Access Journal |
| issn | 2541-9420 2587-9596 |
| language | Russian |
| last_indexed | 2024-04-24T17:19:31Z |
| publishDate | 2016-07-01 |
| publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
| record_format | Article |
| series | Acta Biomedica Scientifica |
| spelling | doaj.art-a0e1fdbbcb1141ea99650aa4b78bcac22024-03-28T07:49:16ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962016-07-011410410810.12737/22978251Effect of intraosseous introduction of selenium/arabinogalactan nanoglycoconjugate on the main indicators of primary metabolism in consolidation of bone fractureL. V. Rodionova0I. A. Shurygina1L. G. Samoylova2B. G. Sukhov3M. G. Shurygin4Irkutsk Scientific Center of Surgery and Traumatology; Irkutsk State Medical Academy of Continuing EducationIrkutsk Scientific Center of Surgery and Traumatology; Irkutsk Scientific Center SB RASIrkutsk Scientific Center of Surgery and TraumatologyA.E. Favorsky Irkutsk Institute of Chemistry SB RASIrkutsk Scientific Center of Surgery and Traumatology; Irkutsk Scientific Center SB RASThe research was carried out on 9 rabbits (males) of Chinchilla breed with modeling of standard perforating fracture of femoral bone. We performed intraosseous introduction of nanocomposite elemental selenium and heteropolysaccharide arabinogalactan 50 mg Se/kg to individuals of experimental group (n = 3) and NaCl 0,9 % to individuals of control group (n = 6). It was established that local intraosseous introduction of the nanocomposite with perforated fracture model did not affect basal metabolic indicators (body temperature, oxygen consumption, carbon dioxide production), but boosted the metabolic processes in the area of the surgical wound from the 9th to 21st days. It proves the bioavailability of the drug and the possibility of creating a local depot of selenium using a nanocomposite.https://www.actabiomedica.ru/jour/article/view/251selenium nanocompositereparative regenerationbasal metabolismthermographybone fracture |
| spellingShingle | L. V. Rodionova I. A. Shurygina L. G. Samoylova B. G. Sukhov M. G. Shurygin Effect of intraosseous introduction of selenium/arabinogalactan nanoglycoconjugate on the main indicators of primary metabolism in consolidation of bone fracture Acta Biomedica Scientifica selenium nanocomposite reparative regeneration basal metabolism thermography bone fracture |
| title | Effect of intraosseous introduction of selenium/arabinogalactan nanoglycoconjugate on the main indicators of primary metabolism in consolidation of bone fracture |
| title_full | Effect of intraosseous introduction of selenium/arabinogalactan nanoglycoconjugate on the main indicators of primary metabolism in consolidation of bone fracture |
| title_fullStr | Effect of intraosseous introduction of selenium/arabinogalactan nanoglycoconjugate on the main indicators of primary metabolism in consolidation of bone fracture |
| title_full_unstemmed | Effect of intraosseous introduction of selenium/arabinogalactan nanoglycoconjugate on the main indicators of primary metabolism in consolidation of bone fracture |
| title_short | Effect of intraosseous introduction of selenium/arabinogalactan nanoglycoconjugate on the main indicators of primary metabolism in consolidation of bone fracture |
| title_sort | effect of intraosseous introduction of selenium arabinogalactan nanoglycoconjugate on the main indicators of primary metabolism in consolidation of bone fracture |
| topic | selenium nanocomposite reparative regeneration basal metabolism thermography bone fracture |
| url | https://www.actabiomedica.ru/jour/article/view/251 |
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