Safety of chromium‐enriched biomass of Yarrowia lipolytica as a novel food pursuant to Regulation (EU) 2015/2283
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on chromium‐enriched biomass of Yarrowia lipolytica as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is the dried and heat‐ki...
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| Format: | Article |
| Language: | English |
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Wiley
2020-03-01
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| Series: | EFSA Journal |
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| Online Access: | https://doi.org/10.2903/j.efsa.2020.6005 |
| _version_ | 1831751247083864064 |
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| author | EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) Dominique Turck Jacqueline Castenmiller Stefaan De Henauw Karen Ildico Hirsch‐Ernst John Kearney Alexandre Maciuk Inge Mangelsdorf Harry J McArdle Androniki Naska Carmen Pelaez Kristina Pentieva Alfonso Siani Frank Thies Sophia Tsabouri Marco Vinceti Francesco Cubadda Karl Heinz Engel Thomas Frenzel Marina Heinonen Rosangela Marchelli Monika Neuhäuser‐Berthold Morten Poulsen Yolanda Sanz Josef Rudolf Schlatter Henk van Loveren Reinhard Ackerl Helle Katrine Knutsen |
| author_facet | EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) Dominique Turck Jacqueline Castenmiller Stefaan De Henauw Karen Ildico Hirsch‐Ernst John Kearney Alexandre Maciuk Inge Mangelsdorf Harry J McArdle Androniki Naska Carmen Pelaez Kristina Pentieva Alfonso Siani Frank Thies Sophia Tsabouri Marco Vinceti Francesco Cubadda Karl Heinz Engel Thomas Frenzel Marina Heinonen Rosangela Marchelli Monika Neuhäuser‐Berthold Morten Poulsen Yolanda Sanz Josef Rudolf Schlatter Henk van Loveren Reinhard Ackerl Helle Katrine Knutsen |
| author_sort | EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) |
| collection | DOAJ |
| description | Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on chromium‐enriched biomass of Yarrowia lipolytica as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is the dried and heat‐killed chromium‐enriched biomass of Y. lipolytica. This yeast species is widespread in nature, can be found in the environment and in foods, and was attributed the qualified presumption of safety (QPS) status for production purposes in 2018, including food and feed products based on biomass of the yeast. The production process, fermentation in the presence of chromium chloride, includes a heat‐killing step of the yeast, resulting in the absence of viable Y. lipolytica in the NF. The maximum total chromium content of the NF is 23 μg Cr/g, with the chromium present as Cr(III). The applicant proposed to use the NF as a food supplement. The target population proposed by the applicant is the general population from 3 years of age onwards, with maximum proposed use levels of 2 g/day for children from 3 to 9 years of age and 4 g/day thereafter. At the proposed use levels of the NF, the combined intake of chromium provided by the NF, in addition to a background diet high in chromium, would result in total chromium intakes well below the tolerable daily intake (TDI) for chromium(III) for all target population groups. The Panel concludes that the NF, chromium‐enriched biomass of Y. lipolytica, is safe under the proposed conditions of use. |
| first_indexed | 2024-12-21T22:41:23Z |
| format | Article |
| id | doaj.art-a0e99fe93148481697e488bfce923f67 |
| institution | Directory Open Access Journal |
| issn | 1831-4732 |
| language | English |
| last_indexed | 2024-12-21T22:41:23Z |
| publishDate | 2020-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | EFSA Journal |
| spelling | doaj.art-a0e99fe93148481697e488bfce923f672022-12-21T18:47:50ZengWileyEFSA Journal1831-47322020-03-01183n/an/a10.2903/j.efsa.2020.6005Safety of chromium‐enriched biomass of Yarrowia lipolytica as a novel food pursuant to Regulation (EU) 2015/2283EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA)Dominique TurckJacqueline CastenmillerStefaan De HenauwKaren Ildico Hirsch‐ErnstJohn KearneyAlexandre MaciukInge MangelsdorfHarry J McArdleAndroniki NaskaCarmen PelaezKristina PentievaAlfonso SianiFrank ThiesSophia TsabouriMarco VincetiFrancesco CubaddaKarl Heinz EngelThomas FrenzelMarina HeinonenRosangela MarchelliMonika Neuhäuser‐BertholdMorten PoulsenYolanda SanzJosef Rudolf SchlatterHenk van LoverenReinhard AckerlHelle Katrine KnutsenAbstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on chromium‐enriched biomass of Yarrowia lipolytica as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is the dried and heat‐killed chromium‐enriched biomass of Y. lipolytica. This yeast species is widespread in nature, can be found in the environment and in foods, and was attributed the qualified presumption of safety (QPS) status for production purposes in 2018, including food and feed products based on biomass of the yeast. The production process, fermentation in the presence of chromium chloride, includes a heat‐killing step of the yeast, resulting in the absence of viable Y. lipolytica in the NF. The maximum total chromium content of the NF is 23 μg Cr/g, with the chromium present as Cr(III). The applicant proposed to use the NF as a food supplement. The target population proposed by the applicant is the general population from 3 years of age onwards, with maximum proposed use levels of 2 g/day for children from 3 to 9 years of age and 4 g/day thereafter. At the proposed use levels of the NF, the combined intake of chromium provided by the NF, in addition to a background diet high in chromium, would result in total chromium intakes well below the tolerable daily intake (TDI) for chromium(III) for all target population groups. The Panel concludes that the NF, chromium‐enriched biomass of Y. lipolytica, is safe under the proposed conditions of use.https://doi.org/10.2903/j.efsa.2020.6005chromium‐enrichedYarrowia lipolyticayeastnovel foodsafety |
| spellingShingle | EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) Dominique Turck Jacqueline Castenmiller Stefaan De Henauw Karen Ildico Hirsch‐Ernst John Kearney Alexandre Maciuk Inge Mangelsdorf Harry J McArdle Androniki Naska Carmen Pelaez Kristina Pentieva Alfonso Siani Frank Thies Sophia Tsabouri Marco Vinceti Francesco Cubadda Karl Heinz Engel Thomas Frenzel Marina Heinonen Rosangela Marchelli Monika Neuhäuser‐Berthold Morten Poulsen Yolanda Sanz Josef Rudolf Schlatter Henk van Loveren Reinhard Ackerl Helle Katrine Knutsen Safety of chromium‐enriched biomass of Yarrowia lipolytica as a novel food pursuant to Regulation (EU) 2015/2283 EFSA Journal chromium‐enriched Yarrowia lipolytica yeast novel food safety |
| title | Safety of chromium‐enriched biomass of Yarrowia lipolytica as a novel food pursuant to Regulation (EU) 2015/2283 |
| title_full | Safety of chromium‐enriched biomass of Yarrowia lipolytica as a novel food pursuant to Regulation (EU) 2015/2283 |
| title_fullStr | Safety of chromium‐enriched biomass of Yarrowia lipolytica as a novel food pursuant to Regulation (EU) 2015/2283 |
| title_full_unstemmed | Safety of chromium‐enriched biomass of Yarrowia lipolytica as a novel food pursuant to Regulation (EU) 2015/2283 |
| title_short | Safety of chromium‐enriched biomass of Yarrowia lipolytica as a novel food pursuant to Regulation (EU) 2015/2283 |
| title_sort | safety of chromium enriched biomass of yarrowia lipolytica as a novel food pursuant to regulation eu 2015 2283 |
| topic | chromium‐enriched Yarrowia lipolytica yeast novel food safety |
| url | https://doi.org/10.2903/j.efsa.2020.6005 |
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