Malignant retroperitoneal solitary fibrous tumor co-existing with Meigs’ syndrome: A case report
Malignant solitary fibrous tumors in the retroperitoneum are rare, and their treatment strategies have not yet been established. A 61-year-old woman with dyspnea underwent laparotomy under a presumptive diagnosis of Meigs’ syndrome. She underwent both adnexectomy and retroperitoneal tumor excision....
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-12-01
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| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043323007136 |
| _version_ | 1797653634650996736 |
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| author | Mikio Takehara Keisuke Ashihara Tomomi Fukunishi Seigo Ibuchi Yukari Mukai |
| author_facet | Mikio Takehara Keisuke Ashihara Tomomi Fukunishi Seigo Ibuchi Yukari Mukai |
| author_sort | Mikio Takehara |
| collection | DOAJ |
| description | Malignant solitary fibrous tumors in the retroperitoneum are rare, and their treatment strategies have not yet been established. A 61-year-old woman with dyspnea underwent laparotomy under a presumptive diagnosis of Meigs’ syndrome. She underwent both adnexectomy and retroperitoneal tumor excision. The histologic diagnosis was of a fibrothecoma of both ovaries and a retroperitoneal solitary fibrous tumor that was considered malignant based on its mitotic activity. Local recurrence was observed 9 months postoperatively; re-excision was performed, and radiation therapy was administered. Four months later, metastasis to the left lung was detected, and a thoracoscopic resection was performed. Although pazopanib was administered subsequently, it was discontinued after 11 months because of proteinuria. She complained of dysphagia 3 weeks after the withdrawal of the drug, and a metastatic tumor was observed at the cranial base. Radiotherapy was initiated; however, she died of the disease 35 months after the primary surgery. Medical guidelines should be established for malignant solitary fibrous tumors to improve patient prognosis. |
| first_indexed | 2024-03-11T16:47:24Z |
| format | Article |
| id | doaj.art-a0ea1d839fc94b699a01370bc7ed4e37 |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-03-11T16:47:24Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-a0ea1d839fc94b699a01370bc7ed4e372023-10-22T04:48:54ZengElsevierRadiology Case Reports1930-04332023-12-01181245534557Malignant retroperitoneal solitary fibrous tumor co-existing with Meigs’ syndrome: A case reportMikio Takehara0Keisuke Ashihara1Tomomi Fukunishi2Seigo Ibuchi3Yukari Mukai4Corresponding author.; Department of Obstetrics and Gynecology, Ikeda City Hospital, 3-1-18 Jyonan, Ikeda City, Osaka 563-8510, JapanDepartment of Obstetrics and Gynecology, Ikeda City Hospital, 3-1-18 Jyonan, Ikeda City, Osaka 563-8510, JapanDepartment of Obstetrics and Gynecology, Ikeda City Hospital, 3-1-18 Jyonan, Ikeda City, Osaka 563-8510, JapanDepartment of Obstetrics and Gynecology, Ikeda City Hospital, 3-1-18 Jyonan, Ikeda City, Osaka 563-8510, JapanDepartment of Obstetrics and Gynecology, Ikeda City Hospital, 3-1-18 Jyonan, Ikeda City, Osaka 563-8510, JapanMalignant solitary fibrous tumors in the retroperitoneum are rare, and their treatment strategies have not yet been established. A 61-year-old woman with dyspnea underwent laparotomy under a presumptive diagnosis of Meigs’ syndrome. She underwent both adnexectomy and retroperitoneal tumor excision. The histologic diagnosis was of a fibrothecoma of both ovaries and a retroperitoneal solitary fibrous tumor that was considered malignant based on its mitotic activity. Local recurrence was observed 9 months postoperatively; re-excision was performed, and radiation therapy was administered. Four months later, metastasis to the left lung was detected, and a thoracoscopic resection was performed. Although pazopanib was administered subsequently, it was discontinued after 11 months because of proteinuria. She complained of dysphagia 3 weeks after the withdrawal of the drug, and a metastatic tumor was observed at the cranial base. Radiotherapy was initiated; however, she died of the disease 35 months after the primary surgery. Medical guidelines should be established for malignant solitary fibrous tumors to improve patient prognosis.http://www.sciencedirect.com/science/article/pii/S1930043323007136Computed tomographyMalignant solitary fibrous tumorMeigs’ syndromeMultidisciplinary treatmentRetroperitoneum |
| spellingShingle | Mikio Takehara Keisuke Ashihara Tomomi Fukunishi Seigo Ibuchi Yukari Mukai Malignant retroperitoneal solitary fibrous tumor co-existing with Meigs’ syndrome: A case report Radiology Case Reports Computed tomography Malignant solitary fibrous tumor Meigs’ syndrome Multidisciplinary treatment Retroperitoneum |
| title | Malignant retroperitoneal solitary fibrous tumor co-existing with Meigs’ syndrome: A case report |
| title_full | Malignant retroperitoneal solitary fibrous tumor co-existing with Meigs’ syndrome: A case report |
| title_fullStr | Malignant retroperitoneal solitary fibrous tumor co-existing with Meigs’ syndrome: A case report |
| title_full_unstemmed | Malignant retroperitoneal solitary fibrous tumor co-existing with Meigs’ syndrome: A case report |
| title_short | Malignant retroperitoneal solitary fibrous tumor co-existing with Meigs’ syndrome: A case report |
| title_sort | malignant retroperitoneal solitary fibrous tumor co existing with meigs syndrome a case report |
| topic | Computed tomography Malignant solitary fibrous tumor Meigs’ syndrome Multidisciplinary treatment Retroperitoneum |
| url | http://www.sciencedirect.com/science/article/pii/S1930043323007136 |
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