New MEMS Tweezers for the Viscoelastic Characterization of Soft Materials at the Microscale
As many studies show, there is a relation between the tissue’s mechanical characteristics and some specific diseases. Knowing this relationship would help early diagnosis or microsurgery. In this paper, a new method for measuring the viscoelastic properties of soft materials at the microscale is pro...
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-12-01
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| Series: | Micromachines |
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| Online Access: | https://www.mdpi.com/2072-666X/9/1/15 |
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| author | Paolo Di Giamberardino Alvise Bagolini Pierluigi Bellutti Imre J. Rudas Matteo Verotti Fabio Botta Nicola P. Belfiore |
| author_facet | Paolo Di Giamberardino Alvise Bagolini Pierluigi Bellutti Imre J. Rudas Matteo Verotti Fabio Botta Nicola P. Belfiore |
| author_sort | Paolo Di Giamberardino |
| collection | DOAJ |
| description | As many studies show, there is a relation between the tissue’s mechanical characteristics and some specific diseases. Knowing this relationship would help early diagnosis or microsurgery. In this paper, a new method for measuring the viscoelastic properties of soft materials at the microscale is proposed. This approach is based on the adoption of a microsystem whose mechanical structure can be reduced to a compliant four bar linkage where the connecting rod is substituted by the tissue sample. A procedure to identify both stiffness and damping coefficients of the tissue is then applied to the developed hardware. Particularly, stiffness is calculated solving the static equations of the mechanism in a desired configuration, while the damping coefficient is inferred from the dynamic equations, which are written under the hypothesis that the sample tissue is excited by a variable compression force characterized by a suitable wave form. The whole procedure is implemented by making use of a control system. |
| first_indexed | 2024-12-11T13:26:08Z |
| format | Article |
| id | doaj.art-a0ecb15120d147c59db10e34307eee0f |
| institution | Directory Open Access Journal |
| issn | 2072-666X |
| language | English |
| last_indexed | 2024-12-11T13:26:08Z |
| publishDate | 2017-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Micromachines |
| spelling | doaj.art-a0ecb15120d147c59db10e34307eee0f2022-12-22T01:05:33ZengMDPI AGMicromachines2072-666X2017-12-01911510.3390/mi9010015mi9010015New MEMS Tweezers for the Viscoelastic Characterization of Soft Materials at the MicroscalePaolo Di Giamberardino0Alvise Bagolini1Pierluigi Bellutti2Imre J. Rudas3Matteo Verotti4Fabio Botta5Nicola P. Belfiore6Department of Computer, Control, and Management Engineering Antonio Ruberti, University of Rome La Sapienza, Via Ariosto 25, I-00185 Roma, ItalyMNF - Micro nano fabrication and characterization Facility, Fondazione Bruno Kessler (FBK), Via Sommarive 18, I-38123 Trento, ItalyMNF - Micro nano fabrication and characterization Facility, Fondazione Bruno Kessler (FBK), Via Sommarive 18, I-38123 Trento, ItalyHead of Steering Committee of University Research and Innovation Center, Óbuda University, 96/b Becsi ut, H-1034 Budapest, HungaryDepartment of Industrial Engineering, University of Trento, via Sommarive, 9-38123 Trento, ItalyDepartment of Engineering, Universita degli Studi Roma Tre, via della Vasca Navale 79, 00146 Roma, ItalyDepartment of Engineering, Universita degli Studi Roma Tre, via della Vasca Navale 79, 00146 Roma, ItalyAs many studies show, there is a relation between the tissue’s mechanical characteristics and some specific diseases. Knowing this relationship would help early diagnosis or microsurgery. In this paper, a new method for measuring the viscoelastic properties of soft materials at the microscale is proposed. This approach is based on the adoption of a microsystem whose mechanical structure can be reduced to a compliant four bar linkage where the connecting rod is substituted by the tissue sample. A procedure to identify both stiffness and damping coefficients of the tissue is then applied to the developed hardware. Particularly, stiffness is calculated solving the static equations of the mechanism in a desired configuration, while the damping coefficient is inferred from the dynamic equations, which are written under the hypothesis that the sample tissue is excited by a variable compression force characterized by a suitable wave form. The whole procedure is implemented by making use of a control system.https://www.mdpi.com/2072-666X/9/1/15MEMStweezerscontrolviscous coefficientsoft tissue |
| spellingShingle | Paolo Di Giamberardino Alvise Bagolini Pierluigi Bellutti Imre J. Rudas Matteo Verotti Fabio Botta Nicola P. Belfiore New MEMS Tweezers for the Viscoelastic Characterization of Soft Materials at the Microscale Micromachines MEMS tweezers control viscous coefficient soft tissue |
| title | New MEMS Tweezers for the Viscoelastic Characterization of Soft Materials at the Microscale |
| title_full | New MEMS Tweezers for the Viscoelastic Characterization of Soft Materials at the Microscale |
| title_fullStr | New MEMS Tweezers for the Viscoelastic Characterization of Soft Materials at the Microscale |
| title_full_unstemmed | New MEMS Tweezers for the Viscoelastic Characterization of Soft Materials at the Microscale |
| title_short | New MEMS Tweezers for the Viscoelastic Characterization of Soft Materials at the Microscale |
| title_sort | new mems tweezers for the viscoelastic characterization of soft materials at the microscale |
| topic | MEMS tweezers control viscous coefficient soft tissue |
| url | https://www.mdpi.com/2072-666X/9/1/15 |
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