Aneuploidy in sperm of fertile men and patients with impaired fertility
The review presents generalized current data on sperm aneuploidy in healthy (fertile) men and infertile male patients with a normal karyotype and with chromosomal abnormalities. The mechanisms of aneuploidy in germ cells, factors affecting of its level, the relationship with defects of spermatogenes...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
ABV-press
2021-12-01
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| Series: | Андрология и генитальная хирургия |
| Subjects: | |
| Online Access: | https://agx.abvpress.ru/jour/article/view/519 |
| _version_ | 1797883515575992320 |
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| author | A. O. Sedova A. I. Martemyanova V. B. Chernykh |
| author_facet | A. O. Sedova A. I. Martemyanova V. B. Chernykh |
| author_sort | A. O. Sedova |
| collection | DOAJ |
| description | The review presents generalized current data on sperm aneuploidy in healthy (fertile) men and infertile male patients with a normal karyotype and with chromosomal abnormalities. The mechanisms of aneuploidy in germ cells, factors affecting of its level, the relationship with defects of spermatogenesis, meiosis, decreased sperm parameters, as well as the effect of sperm aneuploidy on male fertility, embryo development and gestation are discussed. |
| first_indexed | 2024-04-10T03:52:57Z |
| format | Article |
| id | doaj.art-a0effa28cdeb4b4882ca48c25a9b23d6 |
| institution | Directory Open Access Journal |
| issn | 2070-9781 |
| language | Russian |
| last_indexed | 2024-04-10T03:52:57Z |
| publishDate | 2021-12-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Андрология и генитальная хирургия |
| spelling | doaj.art-a0effa28cdeb4b4882ca48c25a9b23d62023-03-13T07:15:11ZrusABV-pressАндрология и генитальная хирургия2070-97812021-12-01224273510.17650/1726-9784-2021-22-4-27-35435Aneuploidy in sperm of fertile men and patients with impaired fertilityA. O. Sedova0A. I. Martemyanova1V. B. Chernykh2N.P. Bochkov Research Centre for Medical GeneticsN.P. Bochkov Research Centre for Medical GeneticsN.P. Bochkov Research Centre for Medical GeneticsThe review presents generalized current data on sperm aneuploidy in healthy (fertile) men and infertile male patients with a normal karyotype and with chromosomal abnormalities. The mechanisms of aneuploidy in germ cells, factors affecting of its level, the relationship with defects of spermatogenesis, meiosis, decreased sperm parameters, as well as the effect of sperm aneuploidy on male fertility, embryo development and gestation are discussed.https://agx.abvpress.ru/jour/article/view/519aneuploidygerm cellsspermatogenesisspermatozoameiosismale infertilityfluorescent hybridization in situ (fish)fertility |
| spellingShingle | A. O. Sedova A. I. Martemyanova V. B. Chernykh Aneuploidy in sperm of fertile men and patients with impaired fertility Андрология и генитальная хирургия aneuploidy germ cells spermatogenesis spermatozoa meiosis male infertility fluorescent hybridization in situ (fish) fertility |
| title | Aneuploidy in sperm of fertile men and patients with impaired fertility |
| title_full | Aneuploidy in sperm of fertile men and patients with impaired fertility |
| title_fullStr | Aneuploidy in sperm of fertile men and patients with impaired fertility |
| title_full_unstemmed | Aneuploidy in sperm of fertile men and patients with impaired fertility |
| title_short | Aneuploidy in sperm of fertile men and patients with impaired fertility |
| title_sort | aneuploidy in sperm of fertile men and patients with impaired fertility |
| topic | aneuploidy germ cells spermatogenesis spermatozoa meiosis male infertility fluorescent hybridization in situ (fish) fertility |
| url | https://agx.abvpress.ru/jour/article/view/519 |
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