Focal Serous Tubal Intra-Epithelial Carcinoma Lesions Are Associated With Global Changes in the Fallopian Tube Epithelia and Stroma

Focal Serous Tubal Intra-Epithelial Carcinoma Lesions Are Associated With Global Changes in the Fallopian Tube Epithelia and Stroma

ObjectiveSerous tubal intra-epithelial carcinoma (STIC) lesions are thought to be precursors to high-grade serous ovarian cancer (HGSOC), but HGSOC is not always accompanied by STIC. Our study was designed to determine if there are global visual and subvisual microenvironmental differences between f...

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Bibliographic Details
Main Authors: Jingni Wu, Yael Raz, Maria Sol Recouvreux, Márcio Augusto Diniz, Jenny Lester, Beth Y. Karlan, Ann E. Walts, Arkadiusz Gertych, Sandra Orsulic
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Oncology
Subjects:
ovarian cancer
fallopian tube
secretory
ciliated
STIC
computational image analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.853755/full

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