Luteolin alleviates inflammation and autophagy of hippocampus induced by cerebral ischemia/reperfusion by activating PPAR gamma in rats

Luteolin alleviates inflammation and autophagy of hippocampus induced by cerebral ischemia/reperfusion by activating PPAR gamma in rats

Abstract Background Luteolin, a flavonoid compound with anti-inflammatory activity, has been reported to alleviate cerebral ischemia/reperfusion (I/R) injury. However, its potential mechanism remains unclear. Methods The binding activity of luteolin to peroxisome proliferator-activated receptor gamm...

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Bibliographic Details
Main Authors: Lu Li, Guanghua Pan, Rong Fan, Dalei Li, Lei Guo, Lili Ma, Hui Liang, Jiaoxue Qiu
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Cerebral ischemia-reperfusion
Pioglitazone
T0070907
Molecular docking analysis
Online Access:https://doi.org/10.1186/s12906-022-03652-8

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