Significant Associations of IgG Glycan Structures With Chronic Graft-Versus-Host Disease Manifestations: Results of the Cross-Sectional NIH Cohort Study

Significant Associations of IgG Glycan Structures With Chronic Graft-Versus-Host Disease Manifestations: Results of the Cross-Sectional NIH Cohort Study

Chronic graft-versus-host disease (cGvHD) is a systemic alloimmune and autoimmune disorder and a major late complication of allogeneic hematopoietic stem cell transplantation (alloHSCT). The disease is characterized by an altered homeostasis of the humoral immune response. Immunoglobulin G (IgG) gly...

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Bibliographic Details
Main Authors: Ema Prenc, Drazen Pulanic, Maja Pucic-Bakovic, Ivo Ugrina, Lana Desnica, Milan Milosevic, Filip Pirsl, Sandra Mitchell, Jeremy Rose, Radovan Vrhovac, Damir Nemet, Gordan Lauc, Steven Z. Pavletic
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
allogeneic hematopoietic stem cell transplantation
chronic graft-versus-host disease
immunoglobulin G
glycans
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.633214/full

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