Marine Collagen Hydrolysates Promote Collagen Synthesis, Viability and Proliferation While Downregulating the Synthesis of Pro-Catabolic Markers in Human Articular Chondrocytes

Marine Collagen Hydrolysates Promote Collagen Synthesis, Viability and Proliferation While Downregulating the Synthesis of Pro-Catabolic Markers in Human Articular Chondrocytes

Cartilage is a non-innervated and non-vascularized tissue. It is composed of one main cell type, the chondrocyte, which governs homeostasis within the cartilage tissue, but has low metabolic activity. Articular cartilage undergoes substantial stresses that lead to chondral defects, and inevitably os...

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Bibliographic Details
Main Authors: Bastien Bourdon, Frédéric Cassé, Nicolas Gruchy, Pierre Cambier, Sylvain Leclercq, Sarah Oddoux, Antoine Noël, Jérôme E. Lafont, Romain Contentin, Philippe Galéra
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
human chondrocytes
matrix-associated autologous chondrocyte implantation (MACI)
osteoarthritis
collagen
collagen hydrolysates
interleukin-1
Online Access:https://www.mdpi.com/1422-0067/22/7/3693

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