Post-kala-azar dermal leishmaniasis associated with AIDS

Post-kala-azar dermal leishmaniasis (PKDL) is rarely reported in South America. In spite of the fact that there are many reports about the association of visceral leishmaniasis and AIDS, PKDL is very uncommon in HIV-positive patients, and so far only four cases have been documented in the literature...

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Main Authors: Achiléa Bittencourt, Nancy Silva, Andréa Straatmann, Victor Luiz Correia Nunes, Ivonise Follador, Roberto Badaró
Format: Article
Language:English
Published: Elsevier
Series:Brazilian Journal of Infectious Diseases
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000600008&lng=en&tlng=en
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author Achiléa Bittencourt
Nancy Silva
Andréa Straatmann
Victor Luiz Correia Nunes
Ivonise Follador
Roberto Badaró
author_facet Achiléa Bittencourt
Nancy Silva
Andréa Straatmann
Victor Luiz Correia Nunes
Ivonise Follador
Roberto Badaró
author_sort Achiléa Bittencourt
collection DOAJ
description Post-kala-azar dermal leishmaniasis (PKDL) is rarely reported in South America. In spite of the fact that there are many reports about the association of visceral leishmaniasis and AIDS, PKDL is very uncommon in HIV-positive patients, and so far only four cases have been documented in the literature. We present another case with unusual clinicopathological aspects. The patient, a 28-year-old male, from Salvador, Bahia (an endemic area) presented with clinical manifestations of visceral leishmaniasis three years after the diagnosis of AIDS. During treatment for visceral leishmaniasis he developed disseminated miliary papules. Microscopically, the skin biopsy showed a "saw-tooth" pattern with a lichenoid mononuclear infiltrate simulating lichen planus. The histopathological diagnosis was achieved through the finding of amastigotes. The authors discuss the clinicopathological aspects of this case based on a review of the specific literature.
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spelling doaj.art-a1041e1fc6c04e51958b33d69bf5a4212022-12-21T19:21:24ZengElsevierBrazilian Journal of Infectious Diseases1678-43916631331610.1590/S1413-86702002000600008S1413-86702002000600008Post-kala-azar dermal leishmaniasis associated with AIDSAchiléa Bittencourt0Nancy Silva1Andréa Straatmann2Victor Luiz Correia Nunes3Ivonise Follador4Roberto Badaró5Hospital Geral Roberto SantosHospital Geral Roberto SantosHospital Geral Roberto SantosHospital Geral Roberto SantosHospital Geral Roberto SantosHospital Geral Roberto SantosPost-kala-azar dermal leishmaniasis (PKDL) is rarely reported in South America. In spite of the fact that there are many reports about the association of visceral leishmaniasis and AIDS, PKDL is very uncommon in HIV-positive patients, and so far only four cases have been documented in the literature. We present another case with unusual clinicopathological aspects. The patient, a 28-year-old male, from Salvador, Bahia (an endemic area) presented with clinical manifestations of visceral leishmaniasis three years after the diagnosis of AIDS. During treatment for visceral leishmaniasis he developed disseminated miliary papules. Microscopically, the skin biopsy showed a "saw-tooth" pattern with a lichenoid mononuclear infiltrate simulating lichen planus. The histopathological diagnosis was achieved through the finding of amastigotes. The authors discuss the clinicopathological aspects of this case based on a review of the specific literature.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000600008&lng=en&tlng=enVisceral leishmaniasispost-kala-azar dermal leishmaniasisAIDS
spellingShingle Achiléa Bittencourt
Nancy Silva
Andréa Straatmann
Victor Luiz Correia Nunes
Ivonise Follador
Roberto Badaró
Post-kala-azar dermal leishmaniasis associated with AIDS
Brazilian Journal of Infectious Diseases
Visceral leishmaniasis
post-kala-azar dermal leishmaniasis
AIDS
title Post-kala-azar dermal leishmaniasis associated with AIDS
title_full Post-kala-azar dermal leishmaniasis associated with AIDS
title_fullStr Post-kala-azar dermal leishmaniasis associated with AIDS
title_full_unstemmed Post-kala-azar dermal leishmaniasis associated with AIDS
title_short Post-kala-azar dermal leishmaniasis associated with AIDS
title_sort post kala azar dermal leishmaniasis associated with aids
topic Visceral leishmaniasis
post-kala-azar dermal leishmaniasis
AIDS
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000600008&lng=en&tlng=en
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