Inferring within-patient HIV-1 evolutionary dynamics under anti-HIV therapy using serial virus samples with vSPA

Inferring within-patient HIV-1 evolutionary dynamics under anti-HIV therapy using serial virus samples with vSPA

<p>Abstract</p> <p>Background</p> <p>Analysis of within-patient HIV evolution under anti-HIV therapy is crucial to a better understanding the possible mechanisms of HIV drug-resistance acquisition. The high evolutionary rate of HIV allows us to trace its evolutionary pr...

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Bibliographic Details
Main Authors: Matsuda Masakazu, Shibata Junko, Sugiura Wataru, Hasegawa Naoki, Ren Fengrong, Tanaka Hiroshi
Format: Article
Language:English
Published: BMC 2009-10-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/10/360

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