Aggressive tumor recurrence after radiofrequency ablation for hepatocellular carcinoma

Image-guided radiofrequency ablation (RFA) is an evolving and growing treatment option for patients with hepatocellular carcinoma (HCC) and hepatic metastasis. RFA offers significant advantages as it is less invasive than surgery and carries a low risk of major complications. However, serious compli...

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Main Authors: Tae Wook Kang, Hyo Keun Lim, Dong Ik Cha
Format: Article
Language:English
Published: Korean Association for the Study of the Liver 2017-03-01
Series:Clinical and Molecular Hepatology
Subjects:
Online Access:http://e-cmh.org/upload/pdf/cmh-2017-0006.pdf
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author Tae Wook Kang
Hyo Keun Lim
Dong Ik Cha
author_facet Tae Wook Kang
Hyo Keun Lim
Dong Ik Cha
author_sort Tae Wook Kang
collection DOAJ
description Image-guided radiofrequency ablation (RFA) is an evolving and growing treatment option for patients with hepatocellular carcinoma (HCC) and hepatic metastasis. RFA offers significant advantages as it is less invasive than surgery and carries a low risk of major complications. However, serious complications, including aggressive tumor recurrence, may be observed during follow-up, and recently, mechanical or thermal damage during RFA has been proposed to be one of the causes of this kind of recurrence. Although the exact mechanism of this still remains unclear, physicians should be familiar with the imaging features of aggressive tumor recurrence after RFA for HCC and its risk factors. In addition, in order to prevent or minimize this newly recognized tumor recurrence, a modified RFA technique, combined RFA treatments with transarterial chemoembolization, and cryoablation can be used as alternative treatments. Ultimately, combining an understanding of this potential complication of RFA with an understanding of the possible risk factors for aggressive tumor recurrence and choosing alternative treatments are crucial to optimize clinical outcomes in each patient with HCC.
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spelling doaj.art-a108e8190fa247d5a7a0c01b33cf02392022-12-22T03:55:39ZengKorean Association for the Study of the LiverClinical and Molecular Hepatology2287-27282287-285X2017-03-012319510110.3350/cmh.2017.00061348Aggressive tumor recurrence after radiofrequency ablation for hepatocellular carcinomaTae Wook KangHyo Keun LimDong Ik ChaImage-guided radiofrequency ablation (RFA) is an evolving and growing treatment option for patients with hepatocellular carcinoma (HCC) and hepatic metastasis. RFA offers significant advantages as it is less invasive than surgery and carries a low risk of major complications. However, serious complications, including aggressive tumor recurrence, may be observed during follow-up, and recently, mechanical or thermal damage during RFA has been proposed to be one of the causes of this kind of recurrence. Although the exact mechanism of this still remains unclear, physicians should be familiar with the imaging features of aggressive tumor recurrence after RFA for HCC and its risk factors. In addition, in order to prevent or minimize this newly recognized tumor recurrence, a modified RFA technique, combined RFA treatments with transarterial chemoembolization, and cryoablation can be used as alternative treatments. Ultimately, combining an understanding of this potential complication of RFA with an understanding of the possible risk factors for aggressive tumor recurrence and choosing alternative treatments are crucial to optimize clinical outcomes in each patient with HCC.http://e-cmh.org/upload/pdf/cmh-2017-0006.pdfLiverHepatocellular carcinomaRadiofrequency ablationTumor recurrence
spellingShingle Tae Wook Kang
Hyo Keun Lim
Dong Ik Cha
Aggressive tumor recurrence after radiofrequency ablation for hepatocellular carcinoma
Clinical and Molecular Hepatology
Liver
Hepatocellular carcinoma
Radiofrequency ablation
Tumor recurrence
title Aggressive tumor recurrence after radiofrequency ablation for hepatocellular carcinoma
title_full Aggressive tumor recurrence after radiofrequency ablation for hepatocellular carcinoma
title_fullStr Aggressive tumor recurrence after radiofrequency ablation for hepatocellular carcinoma
title_full_unstemmed Aggressive tumor recurrence after radiofrequency ablation for hepatocellular carcinoma
title_short Aggressive tumor recurrence after radiofrequency ablation for hepatocellular carcinoma
title_sort aggressive tumor recurrence after radiofrequency ablation for hepatocellular carcinoma
topic Liver
Hepatocellular carcinoma
Radiofrequency ablation
Tumor recurrence
url http://e-cmh.org/upload/pdf/cmh-2017-0006.pdf
work_keys_str_mv AT taewookkang aggressivetumorrecurrenceafterradiofrequencyablationforhepatocellularcarcinoma
AT hyokeunlim aggressivetumorrecurrenceafterradiofrequencyablationforhepatocellularcarcinoma
AT dongikcha aggressivetumorrecurrenceafterradiofrequencyablationforhepatocellularcarcinoma