Model-Based Planning and Delivery of Mass Vaccination Campaigns against Infectious Disease: Application to the COVID-19 Pandemic in the UK
Vaccination plays a key role in reducing morbidity and mortality caused by infectious diseases, including the recent COVID-19 pandemic. However, a comprehensive approach that allows the planning of vaccination campaigns and the estimation of the resources required to deliver and administer COVID-19...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-12-01
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| Series: | Vaccines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-393X/9/12/1460 |
| _version_ | 1797500054391488512 |
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| author | Dauda Ibrahim Zoltán Kis Kyungjae Tak Maria M. Papathanasiou Cleo Kontoravdi Benoît Chachuat Nilay Shah |
| author_facet | Dauda Ibrahim Zoltán Kis Kyungjae Tak Maria M. Papathanasiou Cleo Kontoravdi Benoît Chachuat Nilay Shah |
| author_sort | Dauda Ibrahim |
| collection | DOAJ |
| description | Vaccination plays a key role in reducing morbidity and mortality caused by infectious diseases, including the recent COVID-19 pandemic. However, a comprehensive approach that allows the planning of vaccination campaigns and the estimation of the resources required to deliver and administer COVID-19 vaccines is lacking. This work implements a new framework that supports the planning and delivery of vaccination campaigns. Firstly, the framework segments and priorities target populations, then estimates vaccination timeframe and workforce requirements, and lastly predicts logistics costs and facilitates the distribution of vaccines from manufacturing plants to vaccination centres. The outcomes from this study reveal the necessary resources required and their associated costs ahead of a vaccination campaign. Analysis of results shows that by integrating demand stratification, administration, and the supply chain, the synergy amongst these activities can be exploited to allow planning and cost-effective delivery of a vaccination campaign against COVID-19 and demonstrates how to sustain high rates of vaccination in a resource-efficient fashion. |
| first_indexed | 2024-03-10T03:56:19Z |
| format | Article |
| id | doaj.art-a10938645fd34e7f9e0298e325358ab8 |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-10T03:56:19Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-a10938645fd34e7f9e0298e325358ab82023-11-23T10:54:40ZengMDPI AGVaccines2076-393X2021-12-01912146010.3390/vaccines9121460Model-Based Planning and Delivery of Mass Vaccination Campaigns against Infectious Disease: Application to the COVID-19 Pandemic in the UKDauda Ibrahim0Zoltán Kis1Kyungjae Tak2Maria M. Papathanasiou3Cleo Kontoravdi4Benoît Chachuat5Nilay Shah6The Sargent Centre for Process Systems Engineering, Department of Chemical Engineering, Imperial College London, London SW7 2AZ, UKThe Sargent Centre for Process Systems Engineering, Department of Chemical Engineering, Imperial College London, London SW7 2AZ, UKThe Sargent Centre for Process Systems Engineering, Department of Chemical Engineering, Imperial College London, London SW7 2AZ, UKThe Sargent Centre for Process Systems Engineering, Department of Chemical Engineering, Imperial College London, London SW7 2AZ, UKThe Sargent Centre for Process Systems Engineering, Department of Chemical Engineering, Imperial College London, London SW7 2AZ, UKThe Sargent Centre for Process Systems Engineering, Department of Chemical Engineering, Imperial College London, London SW7 2AZ, UKThe Sargent Centre for Process Systems Engineering, Department of Chemical Engineering, Imperial College London, London SW7 2AZ, UKVaccination plays a key role in reducing morbidity and mortality caused by infectious diseases, including the recent COVID-19 pandemic. However, a comprehensive approach that allows the planning of vaccination campaigns and the estimation of the resources required to deliver and administer COVID-19 vaccines is lacking. This work implements a new framework that supports the planning and delivery of vaccination campaigns. Firstly, the framework segments and priorities target populations, then estimates vaccination timeframe and workforce requirements, and lastly predicts logistics costs and facilitates the distribution of vaccines from manufacturing plants to vaccination centres. The outcomes from this study reveal the necessary resources required and their associated costs ahead of a vaccination campaign. Analysis of results shows that by integrating demand stratification, administration, and the supply chain, the synergy amongst these activities can be exploited to allow planning and cost-effective delivery of a vaccination campaign against COVID-19 and demonstrates how to sustain high rates of vaccination in a resource-efficient fashion.https://www.mdpi.com/2076-393X/9/12/1460SARS-CoV-2 vaccinesvaccination campaignvaccine availabilitydemand stratificationeconomic analysismathematical programming |
| spellingShingle | Dauda Ibrahim Zoltán Kis Kyungjae Tak Maria M. Papathanasiou Cleo Kontoravdi Benoît Chachuat Nilay Shah Model-Based Planning and Delivery of Mass Vaccination Campaigns against Infectious Disease: Application to the COVID-19 Pandemic in the UK Vaccines SARS-CoV-2 vaccines vaccination campaign vaccine availability demand stratification economic analysis mathematical programming |
| title | Model-Based Planning and Delivery of Mass Vaccination Campaigns against Infectious Disease: Application to the COVID-19 Pandemic in the UK |
| title_full | Model-Based Planning and Delivery of Mass Vaccination Campaigns against Infectious Disease: Application to the COVID-19 Pandemic in the UK |
| title_fullStr | Model-Based Planning and Delivery of Mass Vaccination Campaigns against Infectious Disease: Application to the COVID-19 Pandemic in the UK |
| title_full_unstemmed | Model-Based Planning and Delivery of Mass Vaccination Campaigns against Infectious Disease: Application to the COVID-19 Pandemic in the UK |
| title_short | Model-Based Planning and Delivery of Mass Vaccination Campaigns against Infectious Disease: Application to the COVID-19 Pandemic in the UK |
| title_sort | model based planning and delivery of mass vaccination campaigns against infectious disease application to the covid 19 pandemic in the uk |
| topic | SARS-CoV-2 vaccines vaccination campaign vaccine availability demand stratification economic analysis mathematical programming |
| url | https://www.mdpi.com/2076-393X/9/12/1460 |
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