Clinical experience with the use of the intestinal antibiotic Rifaximin for celiac disease
The article is devoted to new possibilities in the treatment of hereditary intestinal diseases, accompanied by a decrease in kinetic activity or the absence of enteric enzymes, including celiac disease. Despite strict adherence to the elimination diet, some patients develop IBS-like symptoms, which...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Remedium Group LLC
2019-10-01
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| Series: | Медицинский совет |
| Subjects: | |
| Online Access: | https://www.med-sovet.pro/jour/article/view/4274 |
| _version_ | 1797841576689401856 |
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| author | L. S. Оrеshkо E. A. Semenova |
| author_facet | L. S. Оrеshkо E. A. Semenova |
| author_sort | L. S. Оrеshkо |
| collection | DOAJ |
| description | The article is devoted to new possibilities in the treatment of hereditary intestinal diseases, accompanied by a decrease in kinetic activity or the absence of enteric enzymes, including celiac disease. Despite strict adherence to the elimination diet, some patients develop IBS-like symptoms, which may be caused by a violation of the qualitative and quantitative composition of the intestinal microflora. Dysbiotic disorders play a role in the pathogenesis of the appearance of IBS-like symptoms and complicate the course of celiac disease, which requires the use of antibacterial drugs. The presence of side effects when using systemic antibacterial drugs limits their use. In this regard, the search for ways to correct the intestinal microflora, as well as the study of various approaches to maintaining the intestinal microecology in a state of physiological equilibrium in patients with celiac disease, are relevant for medical science. The article presents a clinical example of the successful and safe use of a drug with low absorption, high antibacterial activity – rifaximin in a patient with celiac disease to correct dysbiotic disorders. |
| first_indexed | 2024-04-09T16:33:31Z |
| format | Article |
| id | doaj.art-a10d20ea923643198e2d7fb67fe6465b |
| institution | Directory Open Access Journal |
| issn | 2079-701X 2658-5790 |
| language | Russian |
| last_indexed | 2024-04-09T16:33:31Z |
| publishDate | 2019-10-01 |
| publisher | Remedium Group LLC |
| record_format | Article |
| series | Медицинский совет |
| spelling | doaj.art-a10d20ea923643198e2d7fb67fe6465b2023-04-23T06:56:59ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902019-10-01014949810.21518/2079-701X-2019-14-94-983856Clinical experience with the use of the intestinal antibiotic Rifaximin for celiac diseaseL. S. Оrеshkо0E. A. Semenova1North-Western State Medical University named after I.I. MechnikovNorth-Western State Medical University named after I.I. MechnikovThe article is devoted to new possibilities in the treatment of hereditary intestinal diseases, accompanied by a decrease in kinetic activity or the absence of enteric enzymes, including celiac disease. Despite strict adherence to the elimination diet, some patients develop IBS-like symptoms, which may be caused by a violation of the qualitative and quantitative composition of the intestinal microflora. Dysbiotic disorders play a role in the pathogenesis of the appearance of IBS-like symptoms and complicate the course of celiac disease, which requires the use of antibacterial drugs. The presence of side effects when using systemic antibacterial drugs limits their use. In this regard, the search for ways to correct the intestinal microflora, as well as the study of various approaches to maintaining the intestinal microecology in a state of physiological equilibrium in patients with celiac disease, are relevant for medical science. The article presents a clinical example of the successful and safe use of a drug with low absorption, high antibacterial activity – rifaximin in a patient with celiac disease to correct dysbiotic disorders.https://www.med-sovet.pro/jour/article/view/4274celiac diseasedisbiosissmall bowel bacterial overgrowthrifaximin gluten-free diet |
| spellingShingle | L. S. Оrеshkо E. A. Semenova Clinical experience with the use of the intestinal antibiotic Rifaximin for celiac disease Медицинский совет celiac disease disbiosis small bowel bacterial overgrowth rifaximin gluten-free diet |
| title | Clinical experience with the use of the intestinal antibiotic Rifaximin for celiac disease |
| title_full | Clinical experience with the use of the intestinal antibiotic Rifaximin for celiac disease |
| title_fullStr | Clinical experience with the use of the intestinal antibiotic Rifaximin for celiac disease |
| title_full_unstemmed | Clinical experience with the use of the intestinal antibiotic Rifaximin for celiac disease |
| title_short | Clinical experience with the use of the intestinal antibiotic Rifaximin for celiac disease |
| title_sort | clinical experience with the use of the intestinal antibiotic rifaximin for celiac disease |
| topic | celiac disease disbiosis small bowel bacterial overgrowth rifaximin gluten-free diet |
| url | https://www.med-sovet.pro/jour/article/view/4274 |
| work_keys_str_mv | AT lsoreshko clinicalexperiencewiththeuseoftheintestinalantibioticrifaximinforceliacdisease AT easemenova clinicalexperiencewiththeuseoftheintestinalantibioticrifaximinforceliacdisease |