ABCB1 C1236T, G2677T/A and C3435T polymorphisms in systemic lupus erythematosus patients

ABCB1 C1236T, G2677T/A and C3435T polymorphisms in systemic lupus erythematosus patients

P-glycoprotein (Pgp), the ABCB1 gene product, acts as an efflux pump that transports a large variety of substrates and is a mechanism of cell protection against xenobiotics. An increasing number of studies have shown that some ABCB1 polymorphisms may affect Pgp expression and activity, as well as af...

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Bibliographic Details
Main Authors:	T.P. Gonzalez, T. Mucenic, J.C.T. Brenol, R.M. Xavier, M. Schiengold, J.A.B. Chies
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2008-09-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	ABCB1 MDR1 P-glycoprotein Polymorphism Systemic lupus erythematosus
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000900005

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