Animal Models of Coenzyme Q Deficiency: Mechanistic and Translational Learnings

Animal Models of Coenzyme Q Deficiency: Mechanistic and Translational Learnings

Coenzyme Q (CoQ) is a vital lipophilic molecule that is endogenously synthesized in the mitochondria of each cell. The CoQ biosynthetic pathway is complex and not completely characterized, and it involves at least thirteen catalytic and regulatory proteins. Once it is synthesized, CoQ exerts a wide...

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Bibliographic Details
Main Authors: Pilar González-García, Eliana Barriocanal-Casado, María Elena Díaz-Casado, Sergio López-Herrador, Agustín Hidalgo-Gutiérrez, Luis C. López
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Antioxidants
Subjects:
preclinical models
pathomechanisms
therapy
mitochondria
mitochondrial disease
bioenergetics
Online Access:https://www.mdpi.com/2076-3921/10/11/1687

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