High-Throughput Stool Metaproteomics: Method and Application to Human Specimens

High-Throughput Stool Metaproteomics: Method and Application to Human Specimens

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ABSTRACT Stool-based proteomics is capable of significantly augmenting our understanding of host-gut microbe interactions. However, compared to competing technologies, such as metagenomics and 16S rRNA sequencing, it is underutilized due to its low throughput and the negative impact sample contamina...

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Bibliographic Details
Main Authors: Carlos G. Gonzalez, Hannah C. Wastyk, Madeline Topf, Christopher D. Gardner, Justin L. Sonnenburg, Joshua E. Elias
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mSystems
Subjects:
diet
fermented
fiber
high-throughput
mass spectrometry
metaproteomics
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00200-20

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