Transplantation of Organs from Hepatitis C Virus-Positive Donors under Direct-Acting Antiviral Regimens
There is a discrepancy between the patients requiring organ transplants and the donors available to meet that demand. Many patients die every year while on the waiting list, and there is a need to bridge this gap. For many years, medical practitioners have been apprehensive of using donor organs fro...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-01-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/3/770 |
| _version_ | 1797486913057193984 |
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| author | Muhammad Nauman Zahid |
| author_facet | Muhammad Nauman Zahid |
| author_sort | Muhammad Nauman Zahid |
| collection | DOAJ |
| description | There is a discrepancy between the patients requiring organ transplants and the donors available to meet that demand. Many patients die every year while on the waiting list, and there is a need to bridge this gap. For many years, medical practitioners have been apprehensive of using donor organs from donors who have tested positive for the Hepatitis C virus (HCV), and with good reason. HCV has been proven to be among the leading causes of liver diseases requiring liver transplants. Over the years, studies have been carried out to find a treatment for Hepatitis C. The advent of direct-acting antivirals revolutionized the medical world. These medication regimens have been proven to treat Hepatitis C in transplant patients effectively. This systematic review will examine how DAA treatments affect transplants of different organs from HCV-positive donors to HCV-negative recipients. |
| first_indexed | 2024-03-09T23:40:06Z |
| format | Article |
| id | doaj.art-a1143c4431e141c48f8086b88bc2fd83 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T23:40:06Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-a1143c4431e141c48f8086b88bc2fd832023-11-23T16:53:44ZengMDPI AGJournal of Clinical Medicine2077-03832022-01-0111377010.3390/jcm11030770Transplantation of Organs from Hepatitis C Virus-Positive Donors under Direct-Acting Antiviral RegimensMuhammad Nauman Zahid0Department of Biology, College of Science, Sakhir Campus, University of Bahrain, Sakhir P.O. Box 32038, BahrainThere is a discrepancy between the patients requiring organ transplants and the donors available to meet that demand. Many patients die every year while on the waiting list, and there is a need to bridge this gap. For many years, medical practitioners have been apprehensive of using donor organs from donors who have tested positive for the Hepatitis C virus (HCV), and with good reason. HCV has been proven to be among the leading causes of liver diseases requiring liver transplants. Over the years, studies have been carried out to find a treatment for Hepatitis C. The advent of direct-acting antivirals revolutionized the medical world. These medication regimens have been proven to treat Hepatitis C in transplant patients effectively. This systematic review will examine how DAA treatments affect transplants of different organs from HCV-positive donors to HCV-negative recipients.https://www.mdpi.com/2077-0383/11/3/770liver transplantationHepatitis C virusdirect-acting antiviral agentsorgan transplantationHepatitis C infectionHCV-positive donors |
| spellingShingle | Muhammad Nauman Zahid Transplantation of Organs from Hepatitis C Virus-Positive Donors under Direct-Acting Antiviral Regimens Journal of Clinical Medicine liver transplantation Hepatitis C virus direct-acting antiviral agents organ transplantation Hepatitis C infection HCV-positive donors |
| title | Transplantation of Organs from Hepatitis C Virus-Positive Donors under Direct-Acting Antiviral Regimens |
| title_full | Transplantation of Organs from Hepatitis C Virus-Positive Donors under Direct-Acting Antiviral Regimens |
| title_fullStr | Transplantation of Organs from Hepatitis C Virus-Positive Donors under Direct-Acting Antiviral Regimens |
| title_full_unstemmed | Transplantation of Organs from Hepatitis C Virus-Positive Donors under Direct-Acting Antiviral Regimens |
| title_short | Transplantation of Organs from Hepatitis C Virus-Positive Donors under Direct-Acting Antiviral Regimens |
| title_sort | transplantation of organs from hepatitis c virus positive donors under direct acting antiviral regimens |
| topic | liver transplantation Hepatitis C virus direct-acting antiviral agents organ transplantation Hepatitis C infection HCV-positive donors |
| url | https://www.mdpi.com/2077-0383/11/3/770 |
| work_keys_str_mv | AT muhammadnaumanzahid transplantationoforgansfromhepatitiscviruspositivedonorsunderdirectactingantiviralregimens |