Sex-specific role of epigenetic modification of a leptin upstream enhancer in adipose tissue

Sex-specific role of epigenetic modification of a leptin upstream enhancer in adipose tissue

Abstract Objective Maternal hormonal status can have long-term effects on offspring metabolic health and is likely regulated via epigenetic mechanisms. We elucidated the effects of maternal thyroid hormones on the epigenetic regulation of leptin (Lep) transcription in adipose tissue (AT) and subsequ...

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Những tác giả chính:	Luise Müller, Rebecca Oelkrug, Jens Mittag, Anne Hoffmann, Adhideb Ghosh, Falko Noé, Christian Wolfrum, Esther Guiu Jurado, Nora Klöting, Arne Dietrich, Matthias Blüher, Peter Kovacs, Kerstin Krause, Maria Keller
Định dạng:	Bài viết
Ngôn ngữ:	English
Được phát hành:	BMC 2025-02-01
Loạt:	Clinical Epigenetics
Những chủ đề:	Maternal thyroid hormones Body fat Leptin upstream enhancer DNA methylation Sex specific Adipose tissue
Truy cập trực tuyến:	https://doi.org/10.1186/s13148-025-01830-2

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