Experience of eribulin application in previously treated patients with metastatic or locally recurrent breast cancer under the clinical trial
The article deals with the results of the administration of new cytostatic - eribulin (Halaven). In EMBRACE (Eisai Metastatic Breast Cancer Study Assessing Physician's Choice Versus E7389) phase III clinical study, Halaven had been administrated to 6 patients (between 6 and 35 cycles), at that,...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
IP Habib O.N.
2014-09-01
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| Series: | Современная онкология |
| Subjects: | |
| Online Access: | https://modernonco.orscience.ru/1815-1434/article/view/26954 |
| _version_ | 1818041093857476608 |
|---|---|
| author | F Sh Ahmetzanov F F Ahmetzanova |
| author_facet | F Sh Ahmetzanov F F Ahmetzanova |
| author_sort | F Sh Ahmetzanov |
| collection | DOAJ |
| description | The article deals with the results of the administration of new cytostatic - eribulin (Halaven). In EMBRACE (Eisai Metastatic Breast Cancer Study Assessing Physician's Choice Versus E7389) phase III clinical study, Halaven had been administrated to 6 patients (between 6 and 35 cycles), at that, partial tumor regression was observed in 3 patients and other 3 patients achieved stabilization. Median progression-free survival (PFS) was 15,3 months and median duration of response (DOR) was 13 months in eribulin group, in group of treatment of physician's choice - median PFS was 5,3 and median DOR was 3,3 months. This article demonstrates 3 clinical cases. The authors concluded that eribulin showed high effectiveness and meaningful improvement in overall survival, maintaining the high quality of life. |
| first_indexed | 2024-12-10T08:24:57Z |
| format | Article |
| id | doaj.art-a11f603f413e4121b49fc508c402b1e9 |
| institution | Directory Open Access Journal |
| issn | 1815-1434 1815-1442 |
| language | Russian |
| last_indexed | 2024-12-10T08:24:57Z |
| publishDate | 2014-09-01 |
| publisher | IP Habib O.N. |
| record_format | Article |
| series | Современная онкология |
| spelling | doaj.art-a11f603f413e4121b49fc508c402b1e92022-12-22T01:56:16ZrusIP Habib O.N.Современная онкология1815-14341815-14422014-09-01163333824174Experience of eribulin application in previously treated patients with metastatic or locally recurrent breast cancer under the clinical trialF Sh AhmetzanovF F AhmetzanovaThe article deals with the results of the administration of new cytostatic - eribulin (Halaven). In EMBRACE (Eisai Metastatic Breast Cancer Study Assessing Physician's Choice Versus E7389) phase III clinical study, Halaven had been administrated to 6 patients (between 6 and 35 cycles), at that, partial tumor regression was observed in 3 patients and other 3 patients achieved stabilization. Median progression-free survival (PFS) was 15,3 months and median duration of response (DOR) was 13 months in eribulin group, in group of treatment of physician's choice - median PFS was 5,3 and median DOR was 3,3 months. This article demonstrates 3 clinical cases. The authors concluded that eribulin showed high effectiveness and meaningful improvement in overall survival, maintaining the high quality of life.https://modernonco.orscience.ru/1815-1434/article/view/26954breast canceranthracyclinestaxaneshalavenlifetime |
| spellingShingle | F Sh Ahmetzanov F F Ahmetzanova Experience of eribulin application in previously treated patients with metastatic or locally recurrent breast cancer under the clinical trial Современная онкология breast cancer anthracyclines taxanes halaven lifetime |
| title | Experience of eribulin application in previously treated patients with metastatic or locally recurrent breast cancer under the clinical trial |
| title_full | Experience of eribulin application in previously treated patients with metastatic or locally recurrent breast cancer under the clinical trial |
| title_fullStr | Experience of eribulin application in previously treated patients with metastatic or locally recurrent breast cancer under the clinical trial |
| title_full_unstemmed | Experience of eribulin application in previously treated patients with metastatic or locally recurrent breast cancer under the clinical trial |
| title_short | Experience of eribulin application in previously treated patients with metastatic or locally recurrent breast cancer under the clinical trial |
| title_sort | experience of eribulin application in previously treated patients with metastatic or locally recurrent breast cancer under the clinical trial |
| topic | breast cancer anthracyclines taxanes halaven lifetime |
| url | https://modernonco.orscience.ru/1815-1434/article/view/26954 |
| work_keys_str_mv | AT fshahmetzanov experienceoferibulinapplicationinpreviouslytreatedpatientswithmetastaticorlocallyrecurrentbreastcancerundertheclinicaltrial AT ffahmetzanova experienceoferibulinapplicationinpreviouslytreatedpatientswithmetastaticorlocallyrecurrentbreastcancerundertheclinicaltrial |