Antibacterial activity of new atraumatic restorative treatment materials incorporated with Azadirachta indica (Neem) against Streptococcus mutans
Background: The antibacterial property of new atraumatic restorative treatment (ART) materials incorporated with Azadirachta indica (Neem) on Streptococcus mutans was carried out. Materials and methods: The study was carried out by using the agar diffusion method to determine the antibacterial prope...
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| Format: | Article |
| Language: | English |
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Elsevier
2019-10-01
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| Series: | Journal of Oral Biology and Craniofacial Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2212426818302471 |
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| author | P. Divya Kumari Shilpa M. Shenoy Shahnawaz Khijmatgar Avidyuti Chowdhury Edward Lynch Chitta R. Chowdhury |
| author_facet | P. Divya Kumari Shilpa M. Shenoy Shahnawaz Khijmatgar Avidyuti Chowdhury Edward Lynch Chitta R. Chowdhury |
| author_sort | P. Divya Kumari |
| collection | DOAJ |
| description | Background: The antibacterial property of new atraumatic restorative treatment (ART) materials incorporated with Azadirachta indica (Neem) on Streptococcus mutans was carried out. Materials and methods: The study was carried out by using the agar diffusion method to determine the antibacterial property of ART materials (ART-I and ART-II). The zone of inhibition was tabulated, and the data was statistically analyzed using the student t-test. The minimum inhibitory concentrations (MIC) and the minimum bactericidal concentrations (MBC) of the ethanolic extract of Neem were recorded. Results: The MIC and MBC of the mixture of the ethanolic extract of Neem was 3.13% and 12.5% respectively. The zone of inhibition of ART-I and ART-II was 11.81 mm and 11.97 mm respectively. Significant differences were observed between these two ART materials (P = 0,08). Conclusion: Both the new ART materials i.e. ART-I and ART–II have considerable antibacterial activity against S. mutans. |
| first_indexed | 2025-02-18T03:27:02Z |
| format | Article |
| id | doaj.art-a122a4d134244c14aee104b3f6e71316 |
| institution | Directory Open Access Journal |
| issn | 2212-4268 |
| language | English |
| last_indexed | 2025-02-18T03:27:02Z |
| publishDate | 2019-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Oral Biology and Craniofacial Research |
| spelling | doaj.art-a122a4d134244c14aee104b3f6e713162024-11-23T06:27:42ZengElsevierJournal of Oral Biology and Craniofacial Research2212-42682019-10-0194321325Antibacterial activity of new atraumatic restorative treatment materials incorporated with Azadirachta indica (Neem) against Streptococcus mutansP. Divya Kumari0Shilpa M. Shenoy1Shahnawaz Khijmatgar2Avidyuti Chowdhury3Edward Lynch4Chitta R. Chowdhury5Department of Oral Biology and Genomic Studies, A.B.Shetty Memorial Institute of Dental Sciences, Nitte Deemed to be University, Deralakatte, Mangalore, Karnataka, IndiaCentral Research Laboratory, K.S.Hegde Medical Academy, Nitte Deemed to be University. Deralakatte, Mangalore, Karnataka, IndiaDepartment of Oral Biology and Genomic Studies, A.B.Shetty Memorial Institute of Dental Sciences, Nitte Deemed to be University, Deralakatte, Mangalore, Karnataka, IndiaKings College London, Global Child Health Fund, England, UKProfessor & Head of Dentistry,Warwick Dentistry, Warwick Medical School, Coventry, CV4 7AL, UKDepartment of Oral Biology and Genomic Studies, A.B.Shetty Memorial Institute of Dental Sciences, Nitte Deemed to be University, Deralakatte, Mangalore, Karnataka, India; Corresponding author. Academic Dean, Dissertation lead, City of London Dental School, The University of Bolton, Southgate Campus, UK.Background: The antibacterial property of new atraumatic restorative treatment (ART) materials incorporated with Azadirachta indica (Neem) on Streptococcus mutans was carried out. Materials and methods: The study was carried out by using the agar diffusion method to determine the antibacterial property of ART materials (ART-I and ART-II). The zone of inhibition was tabulated, and the data was statistically analyzed using the student t-test. The minimum inhibitory concentrations (MIC) and the minimum bactericidal concentrations (MBC) of the ethanolic extract of Neem were recorded. Results: The MIC and MBC of the mixture of the ethanolic extract of Neem was 3.13% and 12.5% respectively. The zone of inhibition of ART-I and ART-II was 11.81 mm and 11.97 mm respectively. Significant differences were observed between these two ART materials (P = 0,08). Conclusion: Both the new ART materials i.e. ART-I and ART–II have considerable antibacterial activity against S. mutans.http://www.sciencedirect.com/science/article/pii/S2212426818302471Antibacterial activityARTMinimum inhibition concentration (MIC)Minimum bactericidal concentration (MBC)Neem extractSoxhlet method |
| spellingShingle | P. Divya Kumari Shilpa M. Shenoy Shahnawaz Khijmatgar Avidyuti Chowdhury Edward Lynch Chitta R. Chowdhury Antibacterial activity of new atraumatic restorative treatment materials incorporated with Azadirachta indica (Neem) against Streptococcus mutans Journal of Oral Biology and Craniofacial Research Antibacterial activity ART Minimum inhibition concentration (MIC) Minimum bactericidal concentration (MBC) Neem extract Soxhlet method |
| title | Antibacterial activity of new atraumatic restorative treatment materials incorporated with Azadirachta indica (Neem) against Streptococcus mutans |
| title_full | Antibacterial activity of new atraumatic restorative treatment materials incorporated with Azadirachta indica (Neem) against Streptococcus mutans |
| title_fullStr | Antibacterial activity of new atraumatic restorative treatment materials incorporated with Azadirachta indica (Neem) against Streptococcus mutans |
| title_full_unstemmed | Antibacterial activity of new atraumatic restorative treatment materials incorporated with Azadirachta indica (Neem) against Streptococcus mutans |
| title_short | Antibacterial activity of new atraumatic restorative treatment materials incorporated with Azadirachta indica (Neem) against Streptococcus mutans |
| title_sort | antibacterial activity of new atraumatic restorative treatment materials incorporated with azadirachta indica neem against streptococcus mutans |
| topic | Antibacterial activity ART Minimum inhibition concentration (MIC) Minimum bactericidal concentration (MBC) Neem extract Soxhlet method |
| url | http://www.sciencedirect.com/science/article/pii/S2212426818302471 |
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