Electrical energy by electrode placement for cardioversion of atrial fibrillation: a systematic review and meta-analysis

Objective Electrode patch position may not be critical for success when cardioverting atrial fibrillation (AF), but the relevance of applied electrical energy is unclarified. Our objective was to perform a meta-analysis of randomised trials to examine the dose–response relation between energy level...

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Main Authors: Gregory Y H Lip, Nicklas Vinter, Lars Frost, Søren Paaske Johnsen, Ludovic Trinquart, Mikkel Zacharias Bystrup Holst-Hansen
Format: Article
Language:English
Published: BMJ Publishing Group 2023-11-01
Series:Open Heart
Online Access:https://openheart.bmj.com/content/10/2/e002456.full
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author Gregory Y H Lip
Nicklas Vinter
Lars Frost
Søren Paaske Johnsen
Ludovic Trinquart
Mikkel Zacharias Bystrup Holst-Hansen
author_facet Gregory Y H Lip
Nicklas Vinter
Lars Frost
Søren Paaske Johnsen
Ludovic Trinquart
Mikkel Zacharias Bystrup Holst-Hansen
author_sort Gregory Y H Lip
collection DOAJ
description Objective Electrode patch position may not be critical for success when cardioverting atrial fibrillation (AF), but the relevance of applied electrical energy is unclarified. Our objective was to perform a meta-analysis of randomised trials to examine the dose–response relation between energy level and cardioversion success by electrode position in elective cardioversion.Methods We searched PubMed, Embase, The Cochrane Library, Google Scholar and Scopus Citations. Inclusion criteria were randomised controlled trials using biphasic shock waves and self-adhesive patches, and publication date from 2000 to 2023. We used random-effects dose-response models to meta-analyse the relation between energy level and cardioversion success by anterolateral and anteroposterior position. Random-effects models estimated pooled risk ratios (RR) for cardioversion success after the first and the final shocks between the two electrode positions.Results We included five randomised controlled trials (N=1078). After the first low-energy shock, the electrode position was not significantly associated with the likelihood of successful cardioversion (pooled RR anterolateral vs anteroposterior placement 1.28, 95% CI 0.93 to 1.76, with considerable heterogeneity). After a high-energy final shock, there was no evidence of an association between the electrode position and the cumulative chance of cardioversion success (pooled RR anterolateral vs anteroposterior 1.05, 95% CI 0.97 to 1.14). Regardless of electrode position, cardioversion success was significantly less likely with shock energy levels < 200J compared with 200J.Conclusion Evidence from contemporary randomised trials suggests that higher level of electrical energy is associated with higher conversion rate when cardioverting AF with a biphasic shockwave. Positioning of electrodes can be based on convenience.
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spelling doaj.art-a125491a26e4469cae983ce760f535282024-01-03T17:25:07ZengBMJ Publishing GroupOpen Heart2053-36242023-11-0110210.1136/openhrt-2023-002456Electrical energy by electrode placement for cardioversion of atrial fibrillation: a systematic review and meta-analysisGregory Y H Lip0Nicklas Vinter1Lars Frost2Søren Paaske Johnsen3Ludovic Trinquart4Mikkel Zacharias Bystrup Holst-Hansen5Liverpool Centre of Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart & Chest Hospital, Liverpool, UKDanish Center for Health Services Research, Department of Clinical Medicine, Aalborg University, Aalborg, DenmarkDiagnostic Centre, Silkeborg Regional Hospital, Silkeborg, DenmarkDanish Center for Health Services Research, Department of Clinical Medicine, Aalborg University, Aalborg, DenmarkDanish Center for Health Services Research, Department of Clinical Medicine, Aalborg University, Aalborg, DenmarkDiagnostic Centre, Silkeborg Regional Hospital, Silkeborg, DenmarkObjective Electrode patch position may not be critical for success when cardioverting atrial fibrillation (AF), but the relevance of applied electrical energy is unclarified. Our objective was to perform a meta-analysis of randomised trials to examine the dose–response relation between energy level and cardioversion success by electrode position in elective cardioversion.Methods We searched PubMed, Embase, The Cochrane Library, Google Scholar and Scopus Citations. Inclusion criteria were randomised controlled trials using biphasic shock waves and self-adhesive patches, and publication date from 2000 to 2023. We used random-effects dose-response models to meta-analyse the relation between energy level and cardioversion success by anterolateral and anteroposterior position. Random-effects models estimated pooled risk ratios (RR) for cardioversion success after the first and the final shocks between the two electrode positions.Results We included five randomised controlled trials (N=1078). After the first low-energy shock, the electrode position was not significantly associated with the likelihood of successful cardioversion (pooled RR anterolateral vs anteroposterior placement 1.28, 95% CI 0.93 to 1.76, with considerable heterogeneity). After a high-energy final shock, there was no evidence of an association between the electrode position and the cumulative chance of cardioversion success (pooled RR anterolateral vs anteroposterior 1.05, 95% CI 0.97 to 1.14). Regardless of electrode position, cardioversion success was significantly less likely with shock energy levels < 200J compared with 200J.Conclusion Evidence from contemporary randomised trials suggests that higher level of electrical energy is associated with higher conversion rate when cardioverting AF with a biphasic shockwave. Positioning of electrodes can be based on convenience.https://openheart.bmj.com/content/10/2/e002456.full
spellingShingle Gregory Y H Lip
Nicklas Vinter
Lars Frost
Søren Paaske Johnsen
Ludovic Trinquart
Mikkel Zacharias Bystrup Holst-Hansen
Electrical energy by electrode placement for cardioversion of atrial fibrillation: a systematic review and meta-analysis
Open Heart
title Electrical energy by electrode placement for cardioversion of atrial fibrillation: a systematic review and meta-analysis
title_full Electrical energy by electrode placement for cardioversion of atrial fibrillation: a systematic review and meta-analysis
title_fullStr Electrical energy by electrode placement for cardioversion of atrial fibrillation: a systematic review and meta-analysis
title_full_unstemmed Electrical energy by electrode placement for cardioversion of atrial fibrillation: a systematic review and meta-analysis
title_short Electrical energy by electrode placement for cardioversion of atrial fibrillation: a systematic review and meta-analysis
title_sort electrical energy by electrode placement for cardioversion of atrial fibrillation a systematic review and meta analysis
url https://openheart.bmj.com/content/10/2/e002456.full
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